Harnessing Nanoparticles for Immunomodulation and Vaccines
The first successful use of nanoparticles (NPs) for vaccination was reported almost 40 years ago with a virus-like particle-based vaccine against Hepatitis B. Since then, the term NP has been expanded to accommodate a large number of novel nano-sized particles engineered from a range of materials. T...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-02-01
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| Series: | Vaccines |
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| Online Access: | http://www.mdpi.com/2076-393X/5/1/6 |
| _version_ | 1798035033824428032 |
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| author | Ariane C. Gomes Mona Mohsen Martin F. Bachmann |
| author_facet | Ariane C. Gomes Mona Mohsen Martin F. Bachmann |
| author_sort | Ariane C. Gomes |
| collection | DOAJ |
| description | The first successful use of nanoparticles (NPs) for vaccination was reported almost 40 years ago with a virus-like particle-based vaccine against Hepatitis B. Since then, the term NP has been expanded to accommodate a large number of novel nano-sized particles engineered from a range of materials. The great interest in NPs is likely not only a result of the two successful vaccines against hepatitis B and Human Papilloma Virus (HPV) that use this technology, but also due to the versatility of those small-sized particles, as indicated by the wide range of applications reported so far, ranging from medicinal and cosmetics to purely technical applications. In this review, we will focus on the use of NPs, especially virus-like particles (VLPs), in the field of vaccines and will discuss their employment as vaccines, antigen display platforms, adjuvants and drug delivery systems. |
| first_indexed | 2024-04-11T20:52:36Z |
| format | Article |
| id | doaj.art-30c40ba6de7b4c7c86c7d62de79525bc |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-04-11T20:52:36Z |
| publishDate | 2017-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-30c40ba6de7b4c7c86c7d62de79525bc2022-12-22T04:03:47ZengMDPI AGVaccines2076-393X2017-02-0151610.3390/vaccines5010006vaccines5010006Harnessing Nanoparticles for Immunomodulation and VaccinesAriane C. Gomes0Mona Mohsen1Martin F. Bachmann2The Jenner Institute, Oxford University, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UKThe Jenner Institute, Oxford University, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UKThe Jenner Institute, Oxford University, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, UKThe first successful use of nanoparticles (NPs) for vaccination was reported almost 40 years ago with a virus-like particle-based vaccine against Hepatitis B. Since then, the term NP has been expanded to accommodate a large number of novel nano-sized particles engineered from a range of materials. The great interest in NPs is likely not only a result of the two successful vaccines against hepatitis B and Human Papilloma Virus (HPV) that use this technology, but also due to the versatility of those small-sized particles, as indicated by the wide range of applications reported so far, ranging from medicinal and cosmetics to purely technical applications. In this review, we will focus on the use of NPs, especially virus-like particles (VLPs), in the field of vaccines and will discuss their employment as vaccines, antigen display platforms, adjuvants and drug delivery systems.http://www.mdpi.com/2076-393X/5/1/6nanoparticlesvirus-like particlesimmunogenvaccines |
| spellingShingle | Ariane C. Gomes Mona Mohsen Martin F. Bachmann Harnessing Nanoparticles for Immunomodulation and Vaccines Vaccines nanoparticles virus-like particles immunogen vaccines |
| title | Harnessing Nanoparticles for Immunomodulation and Vaccines |
| title_full | Harnessing Nanoparticles for Immunomodulation and Vaccines |
| title_fullStr | Harnessing Nanoparticles for Immunomodulation and Vaccines |
| title_full_unstemmed | Harnessing Nanoparticles for Immunomodulation and Vaccines |
| title_short | Harnessing Nanoparticles for Immunomodulation and Vaccines |
| title_sort | harnessing nanoparticles for immunomodulation and vaccines |
| topic | nanoparticles virus-like particles immunogen vaccines |
| url | http://www.mdpi.com/2076-393X/5/1/6 |
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