Delayed clearance of hepatitis B surface antigen and development of hepatitis B surface antibody in a chronic hemodialysis patient
The introduction of hepatitis B vaccination and infection control in 1977 has greatly decreased the prevalence of hepatitis B. Currently, approximately 2.8% of the end-stage renal disease population is hepatitis B positive with a presence in 27.7% of the USA hemodialysis (HD) units according to the...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=5;spage=1047;epage=1051;aulast=Treger |
| _version_ | 1818156423610105856 |
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| author | Richard Treger Ramy M Hanna Brian M Lee Eduardo A Lopez James Wilson Dalila Corry |
| author_facet | Richard Treger Ramy M Hanna Brian M Lee Eduardo A Lopez James Wilson Dalila Corry |
| author_sort | Richard Treger |
| collection | DOAJ |
| description | The introduction of hepatitis B vaccination and infection control in 1977 has greatly decreased the prevalence of hepatitis B. Currently, approximately 2.8% of the end-stage renal disease population is hepatitis B positive with a presence in 27.7% of the USA hemodialysis (HD) units according to the Dialysis Outcomes and Practice Patterns Study data. The behavior of hepatitis B infection differs significantly between immunocompetent and immunosuppressed hosts. Immunosuppressed hosts present more subtly with complications of chronic hepatitis B infection, being more challenging to detect. It is also well known that patients with chronic infection on HD have a small chance of clearing the virus. We report here a case of a hepatitis B positive HD patient who underwent spontaneous delayed serological clearance of hepatitis B surface antigen and development of immunity via appearance of hepatitis B surface antibody. This is a rare occurrence, and the few similar reported cases will be discussed. |
| first_indexed | 2024-12-11T14:58:04Z |
| format | Article |
| id | doaj.art-30cb256e2eed4f5cb0f3cadea2fc151d |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-12-11T14:58:04Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-30cb256e2eed4f5cb0f3cadea2fc151d2022-12-22T01:01:15ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422016-01-012751047105110.4103/1319-2442.190886Delayed clearance of hepatitis B surface antigen and development of hepatitis B surface antibody in a chronic hemodialysis patientRichard TregerRamy M HannaBrian M LeeEduardo A LopezJames WilsonDalila CorryThe introduction of hepatitis B vaccination and infection control in 1977 has greatly decreased the prevalence of hepatitis B. Currently, approximately 2.8% of the end-stage renal disease population is hepatitis B positive with a presence in 27.7% of the USA hemodialysis (HD) units according to the Dialysis Outcomes and Practice Patterns Study data. The behavior of hepatitis B infection differs significantly between immunocompetent and immunosuppressed hosts. Immunosuppressed hosts present more subtly with complications of chronic hepatitis B infection, being more challenging to detect. It is also well known that patients with chronic infection on HD have a small chance of clearing the virus. We report here a case of a hepatitis B positive HD patient who underwent spontaneous delayed serological clearance of hepatitis B surface antigen and development of immunity via appearance of hepatitis B surface antibody. This is a rare occurrence, and the few similar reported cases will be discussed.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=5;spage=1047;epage=1051;aulast=Treger |
| spellingShingle | Richard Treger Ramy M Hanna Brian M Lee Eduardo A Lopez James Wilson Dalila Corry Delayed clearance of hepatitis B surface antigen and development of hepatitis B surface antibody in a chronic hemodialysis patient Saudi Journal of Kidney Diseases and Transplantation |
| title | Delayed clearance of hepatitis B surface antigen and development of hepatitis B surface antibody in a chronic hemodialysis patient |
| title_full | Delayed clearance of hepatitis B surface antigen and development of hepatitis B surface antibody in a chronic hemodialysis patient |
| title_fullStr | Delayed clearance of hepatitis B surface antigen and development of hepatitis B surface antibody in a chronic hemodialysis patient |
| title_full_unstemmed | Delayed clearance of hepatitis B surface antigen and development of hepatitis B surface antibody in a chronic hemodialysis patient |
| title_short | Delayed clearance of hepatitis B surface antigen and development of hepatitis B surface antibody in a chronic hemodialysis patient |
| title_sort | delayed clearance of hepatitis b surface antigen and development of hepatitis b surface antibody in a chronic hemodialysis patient |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2016;volume=27;issue=5;spage=1047;epage=1051;aulast=Treger |
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