Membrane Hsp70—A Novel Target for the Isolation of Circulating Tumor Cells After Epithelial-to-Mesenchymal Transition

Membrane Hsp70—A Novel Target for the Isolation of Circulating Tumor Cells After Epithelial-to-Mesenchymal Transition

The presence of circulating tumor cells (CTCs) in the peripheral blood is a pre-requisite for progression, invasion, and metastatic spread of cancer. Consequently, the enumeration and molecular characterization of CTCs from the peripheral blood of patients with solid tumors before, during and after...

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Bibliographic Details
Main Authors: Stephanie Breuninger, Stefan Stangl, Caroline Werner, Wolfgang Sievert, Dominik Lobinger, Gemma A. Foulds, Sarah Wagner, Anja Pickhard, Guido Piontek, Konrad Kokowski, Alan G. Pockley, Gabriele Multhoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Oncology
Subjects:
circulating tumor cells (CTCs)
membrane Hsp70
cmHsp70.1 antibody
EpCAM (CD326)
epithelial-to-mesenchymal transition (EMT)
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00497/full

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