The role of soy in development of breast, ovarian, endometrial and prostate gland cancer
Introduction and purpose Soy as a rich source of isoflavones has become a focus of interest because of its positive health benefits on numerous diseases, particularly hormone-related cancers. The aim of this study was to present the current state of knowledge on the role of soy in the development of...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2021-09-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/35196 |
| _version_ | 1818010185115893760 |
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| author | Marcela Maksymowicz Piotr Machowiec Natalia Baran Małgorzata Piekarska |
| author_facet | Marcela Maksymowicz Piotr Machowiec Natalia Baran Małgorzata Piekarska |
| author_sort | Marcela Maksymowicz |
| collection | DOAJ |
| description | Introduction and purpose
Soy as a rich source of isoflavones has become a focus of interest because of its positive health benefits on numerous diseases, particularly hormone-related cancers. The aim of this study was to present the current state of knowledge on the role of soy in the development of breast, ovarian, endometrial, and prostate gland cancer.
A brief description of the state of knowledge
Soy components reduce inflammation, stress oxidative and inhibit proliferation of breast, ovarian, endometrial, and prostate cancer cells. Isoflavones such as genistein, daidzein, S-equol via activation of estrogen receptors, inhibit aromatase synthesis and may decrease the risk of estrogen-dependent cancers. Moreover, soy food products have the potential toregulate molecular pathways of AR and reduce testosterone levels. It leads to a reduced risk of prostate cancer. Furthermore, increased consumption of soy protein and isoflavones decreased the risk of mortality from cancers.
Conclusions
Soy foods and their isoflavones are associated with reduced carcinogenesis. A higher amount of soy intake can have positive benefits for prevention of cancers including breast, prostate gland, endometrial and ovarian cancer.
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| first_indexed | 2024-04-14T05:52:02Z |
| format | Article |
| id | doaj.art-30ce32b54ecf480d9932d60c88b9d80a |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-14T05:52:02Z |
| publishDate | 2021-09-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-30ce32b54ecf480d9932d60c88b9d80a2022-12-22T02:09:04ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062021-09-0111910.12775/JEHS.2021.11.09.023The role of soy in development of breast, ovarian, endometrial and prostate gland cancerMarcela Maksymowicz0Piotr Machowiec1Natalia Baran2Małgorzata Piekarska3Student Research Circle at the Department of Epidemiology and Clinical Research Methodology, Medical University of LublinStudent Research Circle at the Department of Epidemiology and Clinical Research Methodology, Medical University of LublinStudent Scientific Association at the Department of Endocrinology of the Medical University of LublinStudent Scientific Association at the Department of Endocrinology of the Medical University of LublinIntroduction and purpose Soy as a rich source of isoflavones has become a focus of interest because of its positive health benefits on numerous diseases, particularly hormone-related cancers. The aim of this study was to present the current state of knowledge on the role of soy in the development of breast, ovarian, endometrial, and prostate gland cancer. A brief description of the state of knowledge Soy components reduce inflammation, stress oxidative and inhibit proliferation of breast, ovarian, endometrial, and prostate cancer cells. Isoflavones such as genistein, daidzein, S-equol via activation of estrogen receptors, inhibit aromatase synthesis and may decrease the risk of estrogen-dependent cancers. Moreover, soy food products have the potential toregulate molecular pathways of AR and reduce testosterone levels. It leads to a reduced risk of prostate cancer. Furthermore, increased consumption of soy protein and isoflavones decreased the risk of mortality from cancers. Conclusions Soy foods and their isoflavones are associated with reduced carcinogenesis. A higher amount of soy intake can have positive benefits for prevention of cancers including breast, prostate gland, endometrial and ovarian cancer. https://apcz.umk.pl/JEHS/article/view/35196soysoy isoflavonesbreast cancerovarian cancerendometrial cancerprostate cancer |
| spellingShingle | Marcela Maksymowicz Piotr Machowiec Natalia Baran Małgorzata Piekarska The role of soy in development of breast, ovarian, endometrial and prostate gland cancer Journal of Education, Health and Sport soy soy isoflavones breast cancer ovarian cancer endometrial cancer prostate cancer |
| title | The role of soy in development of breast, ovarian, endometrial and prostate gland cancer |
| title_full | The role of soy in development of breast, ovarian, endometrial and prostate gland cancer |
| title_fullStr | The role of soy in development of breast, ovarian, endometrial and prostate gland cancer |
| title_full_unstemmed | The role of soy in development of breast, ovarian, endometrial and prostate gland cancer |
| title_short | The role of soy in development of breast, ovarian, endometrial and prostate gland cancer |
| title_sort | role of soy in development of breast ovarian endometrial and prostate gland cancer |
| topic | soy soy isoflavones breast cancer ovarian cancer endometrial cancer prostate cancer |
| url | https://apcz.umk.pl/JEHS/article/view/35196 |
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