The highly dynamic nature of bacterial heteroresistance impairs its clinical detection
Bacterial populations can show heteroresistance, where an antibiotic resistant subpopulation is part of a susceptible one. Pereira et al. show in Escherichia coli and Salmonella enterica that disk diffusion, a common antibiotic susceptibility test, underestimates the occurrence of heteroresistance i...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-05-01
|
| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-021-02052-x |
| _version_ | 1818857709423820800 |
|---|---|
| author | Cátia Pereira Jimmy Larsson Karin Hjort Johan Elf Dan I. Andersson |
| author_facet | Cátia Pereira Jimmy Larsson Karin Hjort Johan Elf Dan I. Andersson |
| author_sort | Cátia Pereira |
| collection | DOAJ |
| description | Bacterial populations can show heteroresistance, where an antibiotic resistant subpopulation is part of a susceptible one. Pereira et al. show in Escherichia coli and Salmonella enterica that disk diffusion, a common antibiotic susceptibility test, underestimates the occurrence of heteroresistance in clinical isolates. |
| first_indexed | 2024-12-19T08:44:42Z |
| format | Article |
| id | doaj.art-30d04637977e4da795b0806423d91630 |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-12-19T08:44:42Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-30d04637977e4da795b0806423d916302022-12-21T20:28:49ZengNature PortfolioCommunications Biology2399-36422021-05-014111210.1038/s42003-021-02052-xThe highly dynamic nature of bacterial heteroresistance impairs its clinical detectionCátia Pereira0Jimmy Larsson1Karin Hjort2Johan Elf3Dan I. Andersson4Department of Medical Biochemistry and Microbiology, Uppsala UniversityDepartment of Cell and Molecular Biology, Uppsala UniversityDepartment of Medical Biochemistry and Microbiology, Uppsala UniversityDepartment of Cell and Molecular Biology, Uppsala UniversityDepartment of Medical Biochemistry and Microbiology, Uppsala UniversityBacterial populations can show heteroresistance, where an antibiotic resistant subpopulation is part of a susceptible one. Pereira et al. show in Escherichia coli and Salmonella enterica that disk diffusion, a common antibiotic susceptibility test, underestimates the occurrence of heteroresistance in clinical isolates.https://doi.org/10.1038/s42003-021-02052-x |
| spellingShingle | Cátia Pereira Jimmy Larsson Karin Hjort Johan Elf Dan I. Andersson The highly dynamic nature of bacterial heteroresistance impairs its clinical detection Communications Biology |
| title | The highly dynamic nature of bacterial heteroresistance impairs its clinical detection |
| title_full | The highly dynamic nature of bacterial heteroresistance impairs its clinical detection |
| title_fullStr | The highly dynamic nature of bacterial heteroresistance impairs its clinical detection |
| title_full_unstemmed | The highly dynamic nature of bacterial heteroresistance impairs its clinical detection |
| title_short | The highly dynamic nature of bacterial heteroresistance impairs its clinical detection |
| title_sort | highly dynamic nature of bacterial heteroresistance impairs its clinical detection |
| url | https://doi.org/10.1038/s42003-021-02052-x |
| work_keys_str_mv | AT catiapereira thehighlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT jimmylarsson thehighlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT karinhjort thehighlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT johanelf thehighlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT daniandersson thehighlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT catiapereira highlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT jimmylarsson highlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT karinhjort highlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT johanelf highlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection AT daniandersson highlydynamicnatureofbacterialheteroresistanceimpairsitsclinicaldetection |