HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies

Human immunodeficiency virus type 1 (HIV-1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused two major viral outbreaks during the last century. Two major aspects of HIV-1 and SARS-CoV-2 co-infection have been extensively investigated and deserve attention. First, the impa...

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Main Authors: Chiara Stefani, Tobia Fantoni, Michele Bissoli, Jordan Thomas, Alessandra Ruggiero
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/12/2089
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author Chiara Stefani
Tobia Fantoni
Michele Bissoli
Jordan Thomas
Alessandra Ruggiero
author_facet Chiara Stefani
Tobia Fantoni
Michele Bissoli
Jordan Thomas
Alessandra Ruggiero
author_sort Chiara Stefani
collection DOAJ
description Human immunodeficiency virus type 1 (HIV-1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused two major viral outbreaks during the last century. Two major aspects of HIV-1 and SARS-CoV-2 co-infection have been extensively investigated and deserve attention. First, the impact of the co-infection on the progression of disease caused by HIV-1 or SARS-CoV-2. Second, the impact of the HIV-1 anti-retroviral treatment on SARS-CoV-2 infection. In this review, we aim to summarize and discuss the works produced since the beginning of the SARS-CoV-2 pandemic ranging from clinical studies to in vitro experiments in the context of co-infection and drug development.
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spelling doaj.art-30d109ec4487438d99ffb6f89bc6fe852023-11-24T16:13:20ZengMDPI AGLife2075-17292022-12-011212208910.3390/life12122089HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro StudiesChiara Stefani0Tobia Fantoni1Michele Bissoli2Jordan Thomas3Alessandra Ruggiero4Section of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37134 Verona, ItalySection of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37134 Verona, ItalySection of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37134 Verona, ItalyDepartment of Clinical Infection, Microbiology and Immunology, Institute of Veterinary and Ecological Sciences, University of Liverpool, Liverpool L69 3BX, UKSection of Biology and Genetics, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, 37134 Verona, ItalyHuman immunodeficiency virus type 1 (HIV-1) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have caused two major viral outbreaks during the last century. Two major aspects of HIV-1 and SARS-CoV-2 co-infection have been extensively investigated and deserve attention. First, the impact of the co-infection on the progression of disease caused by HIV-1 or SARS-CoV-2. Second, the impact of the HIV-1 anti-retroviral treatment on SARS-CoV-2 infection. In this review, we aim to summarize and discuss the works produced since the beginning of the SARS-CoV-2 pandemic ranging from clinical studies to in vitro experiments in the context of co-infection and drug development.https://www.mdpi.com/2075-1729/12/12/2089HIV-1SARS-CoV-2co-infectionsanti-retroviral drugs
spellingShingle Chiara Stefani
Tobia Fantoni
Michele Bissoli
Jordan Thomas
Alessandra Ruggiero
HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies
Life
HIV-1
SARS-CoV-2
co-infections
anti-retroviral drugs
title HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies
title_full HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies
title_fullStr HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies
title_full_unstemmed HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies
title_short HIV and SARS-CoV-2 Co-Infection: From Population Study Evidence to In Vitro Studies
title_sort hiv and sars cov 2 co infection from population study evidence to in vitro studies
topic HIV-1
SARS-CoV-2
co-infections
anti-retroviral drugs
url https://www.mdpi.com/2075-1729/12/12/2089
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