In Vitro and Ex Vivo Evaluation of Penetratin as a Non-invasive Permeation Enhancer in the Penetration of Salmon Calcitonin through TR146 Buccal Cells and Porcine Buccal Tissues

In Vitro and Ex Vivo Evaluation of Penetratin as a Non-invasive Permeation Enhancer in the Penetration of Salmon Calcitonin through TR146 Buccal Cells and Porcine Buccal Tissues

Buccal tissues are considered one of the potential alternative delivery route because of fast drug absorption and onset of action due to high vascularization and a non-keratinized epithelial membrane. In this study, the effect of Penetratin on the permeation of salmon calcitonin (sCT), a model macro...

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Bibliographic Details
Main Authors: Taekwang Keum, Gyubin Noh, Jo-Eun Seo, Santosh Bashyal, Sangkil Lee
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pharmaceuticals
Subjects:
cell penetrating peptide
Penetratin
salmon calcitonin
buccal drug delivery
TR146 cells
Online Access:https://www.mdpi.com/1424-8247/13/11/408

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