Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome
Introduction: A variety of maladies, sometimes disabling, beset many ovulatory women in a recurrent manner during the luteal phase of each ovarian cycle. These problems can deteriorate interpersonal relationships and/or interfere with normal activities of life. Present research was performed to eval...
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2004-03-01
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| Series: | حیات |
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| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1001.pdf&manuscript_id=1001 |
| _version_ | 1818904633602473984 |
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| author | Pakgohar M Mehran A Salehi M.S Akhondzadeh Sh Ahmadi M |
| author_facet | Pakgohar M Mehran A Salehi M.S Akhondzadeh Sh Ahmadi M |
| author_sort | Pakgohar M |
| collection | DOAJ |
| description | Introduction: A variety of maladies, sometimes disabling, beset many ovulatory women in a recurrent manner during the luteal phase of each ovarian cycle. These problems can deteriorate interpersonal relationships and/or interfere with normal activities of life. Present research was performed to evaluate effects of hypericum perforatum for treatment of physical symptoms of premenstrual syndrome. Materials and Methods: This study was a randomized, double-blind, placebo-controlled, parallel group compassion study performed over two menstrual cycles on student of Tehran University of Medical Sciences and Tehran University. Volunteers underwent a preliminary screening interview, completed Beck questionnaire as a screening test for depression and attended a medical screening visit before being diagnosed as having premenstrual syndrome. Participants administrated hypericum or placebo, 30 drops BD, for two complete cycles. Premenstrual symptoms were evaluated by a daily symptom report form. Data analysis performed by Chi square, Fisher exact, Wilcoxon and t tests. Results: Premenstrual daily hypericum caused a significant improvement in mean daily score of severity of premenstrual problems compared to placebo (p<0.05). Premenstrual administration of hypericum, 30 drop BD, showed significant advantage over placebo for physical disorders (%49, p=000). Conclusion: Daily premenstrual administration of hypericum perforatum treats physical symptoms of premenstrual syndrome. It seems that hypericum perforatum can improve symptoms of premenstrual syndrome. |
| first_indexed | 2024-12-19T21:10:33Z |
| format | Article |
| id | doaj.art-30d300a11e8346f79c0936edb6c1c252 |
| institution | Directory Open Access Journal |
| issn | 1735-2215 2008-188X |
| language | fas |
| last_indexed | 2024-12-19T21:10:33Z |
| publishDate | 2004-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | حیات |
| spelling | doaj.art-30d300a11e8346f79c0936edb6c1c2522022-12-21T20:05:31ZfasTehran University of Medical Sciencesحیات1735-22152008-188X2004-03-011033137Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndromePakgohar MMehran ASalehi M.SAkhondzadeh ShAhmadi MIntroduction: A variety of maladies, sometimes disabling, beset many ovulatory women in a recurrent manner during the luteal phase of each ovarian cycle. These problems can deteriorate interpersonal relationships and/or interfere with normal activities of life. Present research was performed to evaluate effects of hypericum perforatum for treatment of physical symptoms of premenstrual syndrome. Materials and Methods: This study was a randomized, double-blind, placebo-controlled, parallel group compassion study performed over two menstrual cycles on student of Tehran University of Medical Sciences and Tehran University. Volunteers underwent a preliminary screening interview, completed Beck questionnaire as a screening test for depression and attended a medical screening visit before being diagnosed as having premenstrual syndrome. Participants administrated hypericum or placebo, 30 drops BD, for two complete cycles. Premenstrual symptoms were evaluated by a daily symptom report form. Data analysis performed by Chi square, Fisher exact, Wilcoxon and t tests. Results: Premenstrual daily hypericum caused a significant improvement in mean daily score of severity of premenstrual problems compared to placebo (p<0.05). Premenstrual administration of hypericum, 30 drop BD, showed significant advantage over placebo for physical disorders (%49, p=000). Conclusion: Daily premenstrual administration of hypericum perforatum treats physical symptoms of premenstrual syndrome. It seems that hypericum perforatum can improve symptoms of premenstrual syndrome.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1001.pdf&manuscript_id=1001Premenstrual syndromehypericum perforatumherbal treatment |
| spellingShingle | Pakgohar M Mehran A Salehi M.S Akhondzadeh Sh Ahmadi M Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome حیات Premenstrual syndrome hypericum perforatum herbal treatment |
| title | Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome |
| title_full | Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome |
| title_fullStr | Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome |
| title_full_unstemmed | Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome |
| title_short | Comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome |
| title_sort | comparison of hypericum perforatum and placebo in treatment of physical symptoms of premenstrual syndrome |
| topic | Premenstrual syndrome hypericum perforatum herbal treatment |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/1001.pdf&manuscript_id=1001 |
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