Targeting NLRP3 Inflammasome in the Treatment of CNS Diseases

Targeting NLRP3 Inflammasome in the Treatment of CNS Diseases

Central nervous system (CNS) is one of the largest killers of people’s health all over the world. The overactivation of the immune and inflammatory responses is considered as an important factor, contributing to the pathogenesis and progression of CNS disorders. Among all kinds of immune and inflamm...

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Bibliographic Details
Main Authors: Bo-Zong Shao, Qi Cao, Chong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
NLRP3 inflammasome
CNS diseases
innate immunity
inhibitors
pharmacological application
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2018.00320/full

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