Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID‐19) patients: Is it really pancreatic injury?
Abstract Coronavirus disease 2019 (COVID‐19) is a novel disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Although it mainly affects the respiratory system, the pancreas could also become the virus' target. The issue regarding pancreatic involvement in COVID‐19 ha...
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Format: | Article |
Language: | English |
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Wiley
2021-02-01
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Series: | JGH Open |
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Online Access: | https://doi.org/10.1002/jgh3.12436 |
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author | Rabbinu R Pribadi Marcellus Simadibrata |
author_facet | Rabbinu R Pribadi Marcellus Simadibrata |
author_sort | Rabbinu R Pribadi |
collection | DOAJ |
description | Abstract Coronavirus disease 2019 (COVID‐19) is a novel disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Although it mainly affects the respiratory system, the pancreas could also become the virus' target. The issue regarding pancreatic involvement in COVID‐19 has been raised by several researchers. They found increased serum amylase and/or lipase in COVID‐19 patients, which suggested pancreatic injury. We aimed to critically review the evidence to provide insights and to answer the very question of the possibility of pancreatic injury. Current evidence shows that increased amylase and/or lipase is not necessarily a pancreatic injury in COVID‐19 patients. Those increased enzymes might also be found in other clinical conditions. |
first_indexed | 2024-12-20T12:30:10Z |
format | Article |
id | doaj.art-30d6b36e28a54249abae68cf8140cb63 |
institution | Directory Open Access Journal |
issn | 2397-9070 |
language | English |
last_indexed | 2024-12-20T12:30:10Z |
publishDate | 2021-02-01 |
publisher | Wiley |
record_format | Article |
series | JGH Open |
spelling | doaj.art-30d6b36e28a54249abae68cf8140cb632022-12-21T19:40:45ZengWileyJGH Open2397-90702021-02-015219019210.1002/jgh3.12436Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID‐19) patients: Is it really pancreatic injury?Rabbinu R Pribadi0Marcellus Simadibrata1Division of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia Cipto Mangunkusumo National General Hospital Jakarta IndonesiaDivision of Gastroenterology, Department of Internal Medicine, Faculty of Medicine Universitas Indonesia Cipto Mangunkusumo National General Hospital Jakarta IndonesiaAbstract Coronavirus disease 2019 (COVID‐19) is a novel disorder caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Although it mainly affects the respiratory system, the pancreas could also become the virus' target. The issue regarding pancreatic involvement in COVID‐19 has been raised by several researchers. They found increased serum amylase and/or lipase in COVID‐19 patients, which suggested pancreatic injury. We aimed to critically review the evidence to provide insights and to answer the very question of the possibility of pancreatic injury. Current evidence shows that increased amylase and/or lipase is not necessarily a pancreatic injury in COVID‐19 patients. Those increased enzymes might also be found in other clinical conditions.https://doi.org/10.1002/jgh3.12436amylasesCOVID‐19lipasepancreas |
spellingShingle | Rabbinu R Pribadi Marcellus Simadibrata Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID‐19) patients: Is it really pancreatic injury? JGH Open amylases COVID‐19 lipase pancreas |
title | Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID‐19) patients: Is it really pancreatic injury? |
title_full | Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID‐19) patients: Is it really pancreatic injury? |
title_fullStr | Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID‐19) patients: Is it really pancreatic injury? |
title_full_unstemmed | Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID‐19) patients: Is it really pancreatic injury? |
title_short | Increased serum amylase and/or lipase in coronavirus disease 2019 (COVID‐19) patients: Is it really pancreatic injury? |
title_sort | increased serum amylase and or lipase in coronavirus disease 2019 covid 19 patients is it really pancreatic injury |
topic | amylases COVID‐19 lipase pancreas |
url | https://doi.org/10.1002/jgh3.12436 |
work_keys_str_mv | AT rabbinurpribadi increasedserumamylaseandorlipaseincoronavirusdisease2019covid19patientsisitreallypancreaticinjury AT marcellussimadibrata increasedserumamylaseandorlipaseincoronavirusdisease2019covid19patientsisitreallypancreaticinjury |