Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-Analysis
Background. The aim of the present study was to determine the prevalence and incidence of diabetic retinopathy (DR) and its changes in the last 20 years in type 2 diabetes mellitus (T2DM) patients in Spain. Methods. A systematic review with a meta-analysis was carried out on the studies published be...
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MDPI AG
2022-07-01
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| Online Access: | https://www.mdpi.com/2227-9032/10/7/1318 |
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| author | Pedro Romero-Aroca Maribel López-Galvez Maria Asuncion Martinez-Brocca Alicia Pareja-Ríos Sara Artola Josep Franch-Nadal Joan Fernandez-Ballart José Andonegui Marc Baget-Bernaldiz |
| author_facet | Pedro Romero-Aroca Maribel López-Galvez Maria Asuncion Martinez-Brocca Alicia Pareja-Ríos Sara Artola Josep Franch-Nadal Joan Fernandez-Ballart José Andonegui Marc Baget-Bernaldiz |
| author_sort | Pedro Romero-Aroca |
| collection | DOAJ |
| description | Background. The aim of the present study was to determine the prevalence and incidence of diabetic retinopathy (DR) and its changes in the last 20 years in type 2 diabetes mellitus (T2DM) patients in Spain. Methods. A systematic review with a meta-analysis was carried out on the studies published between 2001–2020 on the prevalence and incidence of DR and sight-threatening diabetic retinopathy (STDR) in Spain. The articles included were selected from four databases and publications of the Spanish Ministry of Health and Regional Health Care System (RHCS). The meta-analysis to determine heterogeneity and bias between studies was carried out with the MetaXL 4.0. Results. Since 2001, we have observed an increase in the detection of patients with DM, and at the same time, screening programs for RD have been launched; thus, we can deduce that the increase in the detection of patients with DM, many of them in the initial phases, far exceeds the increased detection of patients with DR. The prevalence of DR was higher between 2001 and 2008 with values of 28.85%. These values decreased over the following period between 2009 and 2020 with a mean of 15.28%. Similarly the STDR prevalence decrease from 3.67% to 1.92% after 2008. The analysis of the longitudinal studies determined that the annual DR incidence was 3.83%, and the STDR annual incidence was 0.41%. Conclusion. In Spain, for T2DM, the current prevalence of DR is 15.28% and 1.92% forSTDR. The annual incidence of DR is 3.83% and is 0.41% for STDR. |
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| last_indexed | 2024-03-09T03:22:14Z |
| publishDate | 2022-07-01 |
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| series | Healthcare |
| spelling | doaj.art-30d6ec0d80e447dea492dd769423da682023-12-03T15:07:45ZengMDPI AGHealthcare2227-90322022-07-01107131810.3390/healthcare10071318Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-AnalysisPedro Romero-Aroca0Maribel López-Galvez1Maria Asuncion Martinez-Brocca2Alicia Pareja-Ríos3Sara Artola4Josep Franch-Nadal5Joan Fernandez-Ballart6José Andonegui7Marc Baget-Bernaldiz8Ophthalmic Department, University Hospital Sant Joan, Institut de Investigacio Sanitaries Pere Virgili, Universitat Rovira & Virgili, 43204 Reus, SpainOphthalmic Department, IOBA, Hospital Clínico Universitario de Valladolid, 47003 Valladolid, SpainComprehensive Healthcare Plan for Diabetes, Regional Ministry of Health and Families of Andalusia, Government of Andalusia, 14071 Seville, SpainOphthalmic Department, Hospital Universitario de Canarias, Carretera Ofra S/N, 38320 San Cristóbal de La Laguna, SpainFamily Physiacian, Health Care Center Jose Marva, 28020 Madrid, SpainEAP Raval Sud—Gerencia Territorial Barcelona, Institut Catala de la Salut, IDIAP Jordi Gol/CIBERDEM (IIB Sant Pau), 08006 Barcelona, SpainArea of Preventive Medicine and Public Health, Faculty of Medicine and Health Sciences, Institut d’Investigacions Sanitàries Pere i Virgili, Universitat Rovira i Virgili (URV), 43003 Tarragona, SpainDepartment of Ophthalmology, Hospital Universitario de Navarra, IdiSNA, Navarra Institute for Health Research, 31009 Pamplona, SpainOphthalmic Department, University Hospital Sant Joan, Institut de Investigacio Sanitaries Pere Virgili, Universitat Rovira & Virgili, 43204 Reus, SpainBackground. The aim of the present study was to determine the prevalence and incidence of diabetic retinopathy (DR) and its changes in the last 20 years in type 2 diabetes mellitus (T2DM) patients in Spain. Methods. A systematic review with a meta-analysis was carried out on the studies published between 2001–2020 on the prevalence and incidence of DR and sight-threatening diabetic retinopathy (STDR) in Spain. The articles included were selected from four databases and publications of the Spanish Ministry of Health and Regional Health Care System (RHCS). The meta-analysis to determine heterogeneity and bias between studies was carried out with the MetaXL 4.0. Results. Since 2001, we have observed an increase in the detection of patients with DM, and at the same time, screening programs for RD have been launched; thus, we can deduce that the increase in the detection of patients with DM, many of them in the initial phases, far exceeds the increased detection of patients with DR. The prevalence of DR was higher between 2001 and 2008 with values of 28.85%. These values decreased over the following period between 2009 and 2020 with a mean of 15.28%. Similarly the STDR prevalence decrease from 3.67% to 1.92% after 2008. The analysis of the longitudinal studies determined that the annual DR incidence was 3.83%, and the STDR annual incidence was 0.41%. Conclusion. In Spain, for T2DM, the current prevalence of DR is 15.28% and 1.92% forSTDR. The annual incidence of DR is 3.83% and is 0.41% for STDR.https://www.mdpi.com/2227-9032/10/7/1318diabetic retinopathy prevalencediabetic retinopathy incidenceepidemiologydiabetes mellitusscreeningsystematic review |
| spellingShingle | Pedro Romero-Aroca Maribel López-Galvez Maria Asuncion Martinez-Brocca Alicia Pareja-Ríos Sara Artola Josep Franch-Nadal Joan Fernandez-Ballart José Andonegui Marc Baget-Bernaldiz Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-Analysis Healthcare diabetic retinopathy prevalence diabetic retinopathy incidence epidemiology diabetes mellitus screening systematic review |
| title | Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-Analysis |
| title_full | Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-Analysis |
| title_fullStr | Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-Analysis |
| title_short | Changes in the Epidemiology of Diabetic Retinopathy in Spain: A Systematic Review and Meta-Analysis |
| title_sort | changes in the epidemiology of diabetic retinopathy in spain a systematic review and meta analysis |
| topic | diabetic retinopathy prevalence diabetic retinopathy incidence epidemiology diabetes mellitus screening systematic review |
| url | https://www.mdpi.com/2227-9032/10/7/1318 |
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