The role of Saccharomyces cerevisiae to alleviate copper sulfate toxicity in Cyprinus carpio
This study aimed to determine the role of Saccharomyces cerevisiae in alleviating copper sulfate toxicity in carp fish and by evaluating Acetylcholinesterase (AChE) activity and histopathological alteration in gills and brain with determined the severity of lesions in the gills by semi-quantities an...
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| Format: | Article |
| Language: | Arabic |
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University of Mosul, College of Veterinary Medicine
2023-07-01
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| Series: | Iraqi Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | https://www.vetmedmosul.com/article_178782_5723250408b5522064f4601286856872.pdf |
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| author | Shahbaa Kh. Al-Taee Muna H. Al-Zubaidy Khayrea A. Mustafa Hana Kh. Ismail |
| author_facet | Shahbaa Kh. Al-Taee Muna H. Al-Zubaidy Khayrea A. Mustafa Hana Kh. Ismail |
| author_sort | Shahbaa Kh. Al-Taee |
| collection | DOAJ |
| description | This study aimed to determine the role of Saccharomyces cerevisiae in alleviating copper sulfate toxicity in carp fish and by evaluating Acetylcholinesterase (AChE) activity and histopathological alteration in gills and brain with determined the severity of lesions in the gills by semi-quantities analysis. Sixty fish were divided into four groups first was a control group fish in the second group were exposed to CuSO4 0.53 mg/L, in the third group fish were treated with yeast 5 g/ kg ratio and the fourth group fish treated with yeast and exposed to CuSO4. At the end of the experiment (56 days) it was observed that there was a significant decrease in the AChE activity in the second group, while this activity was improved significantly in the fourth group. The histopathological alteration in the brain was variable in the severity from infiltration of inflammatory, edema, and central chromatolysis of neuron cell bodies. At the same time, the lesions in the gills include edema, congestion, hydropic degeneration, hyperplasia in the mucus cells with shortening in the secondary gill filaments shaped like a drumstick, necrosis, and cartilage disruption. The semi-quantities lesions analysis in the gills classified them as mild, moderate, severe, and irreversible lesions. These lesions in both brain and gills were mild in severity in fish of group fourth. These studies conclude that the activity of AChE is a biological indicator for copper sulfate neurotoxicity and also causes damage to the brain and gills, and yeast is a bio adsorbent agent for copper |
| first_indexed | 2024-03-13T02:09:51Z |
| format | Article |
| id | doaj.art-30d84fb54d5c4bb5b5244ad222311c4d |
| institution | Directory Open Access Journal |
| issn | 1607-3894 2071-1255 |
| language | Arabic |
| last_indexed | 2024-03-13T02:09:51Z |
| publishDate | 2023-07-01 |
| publisher | University of Mosul, College of Veterinary Medicine |
| record_format | Article |
| series | Iraqi Journal of Veterinary Sciences |
| spelling | doaj.art-30d84fb54d5c4bb5b5244ad222311c4d2023-07-01T04:41:41ZaraUniversity of Mosul, College of Veterinary MedicineIraqi Journal of Veterinary Sciences1607-38942071-12552023-07-0137357358010.33899/ijvs.2023.135148.2449178782The role of Saccharomyces cerevisiae to alleviate copper sulfate toxicity in Cyprinus carpioShahbaa Kh. Al-Taee0Muna H. Al-Zubaidy1Khayrea A. Mustafa2Hana Kh. Ismail3Department of Pathology and Poultry Diseases, College of Veterinary Medicine, University of Mosul, Mosul, IraqDepartment of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Mosul, Mosul, IraqDepartment of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Mosul, Mosul, IraqDepartment of Pathology and Poultry Diseases, College of Veterinary Medicine, University of Mosul, Mosul, IraqThis study aimed to determine the role of Saccharomyces cerevisiae in alleviating copper sulfate toxicity in carp fish and by evaluating Acetylcholinesterase (AChE) activity and histopathological alteration in gills and brain with determined the severity of lesions in the gills by semi-quantities analysis. Sixty fish were divided into four groups first was a control group fish in the second group were exposed to CuSO4 0.53 mg/L, in the third group fish were treated with yeast 5 g/ kg ratio and the fourth group fish treated with yeast and exposed to CuSO4. At the end of the experiment (56 days) it was observed that there was a significant decrease in the AChE activity in the second group, while this activity was improved significantly in the fourth group. The histopathological alteration in the brain was variable in the severity from infiltration of inflammatory, edema, and central chromatolysis of neuron cell bodies. At the same time, the lesions in the gills include edema, congestion, hydropic degeneration, hyperplasia in the mucus cells with shortening in the secondary gill filaments shaped like a drumstick, necrosis, and cartilage disruption. The semi-quantities lesions analysis in the gills classified them as mild, moderate, severe, and irreversible lesions. These lesions in both brain and gills were mild in severity in fish of group fourth. These studies conclude that the activity of AChE is a biological indicator for copper sulfate neurotoxicity and also causes damage to the brain and gills, and yeast is a bio adsorbent agent for copperhttps://www.vetmedmosul.com/article_178782_5723250408b5522064f4601286856872.pdfyeasthistopathologicalachegillscarp |
| spellingShingle | Shahbaa Kh. Al-Taee Muna H. Al-Zubaidy Khayrea A. Mustafa Hana Kh. Ismail The role of Saccharomyces cerevisiae to alleviate copper sulfate toxicity in Cyprinus carpio Iraqi Journal of Veterinary Sciences yeast histopathological ache gills carp |
| title | The role of Saccharomyces cerevisiae to alleviate copper sulfate toxicity in Cyprinus carpio |
| title_full | The role of Saccharomyces cerevisiae to alleviate copper sulfate toxicity in Cyprinus carpio |
| title_fullStr | The role of Saccharomyces cerevisiae to alleviate copper sulfate toxicity in Cyprinus carpio |
| title_full_unstemmed | The role of Saccharomyces cerevisiae to alleviate copper sulfate toxicity in Cyprinus carpio |
| title_short | The role of Saccharomyces cerevisiae to alleviate copper sulfate toxicity in Cyprinus carpio |
| title_sort | role of saccharomyces cerevisiae to alleviate copper sulfate toxicity in cyprinus carpio |
| topic | yeast histopathological ache gills carp |
| url | https://www.vetmedmosul.com/article_178782_5723250408b5522064f4601286856872.pdf |
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