Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction
This article describes additional data related to a research article entitled “Kinetics of Quadruplex to Duplex Conversion” (Mendoza et al. 2015 [1]). We followed the opening reaction of a series of intramolecular G-quadruplex structures by the addition of their corresponding complementary strand. F...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-12-01
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| Series: | Data in Brief |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340915002875 |
| _version_ | 1828382830196948992 |
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| author | Oscar Mendoza Juan Elezgaray Jean-Louis Mergny |
| author_facet | Oscar Mendoza Juan Elezgaray Jean-Louis Mergny |
| author_sort | Oscar Mendoza |
| collection | DOAJ |
| description | This article describes additional data related to a research article entitled “Kinetics of Quadruplex to Duplex Conversion” (Mendoza et al. 2015 [1]). We followed the opening reaction of a series of intramolecular G-quadruplex structures by the addition of their corresponding complementary strand. Fluorolabeled complementary strands allowed to monitor the reaction in real-time. An adapted kinetic model was then applied in order to obtain the kinetic parameters of this reaction.
We present a series of kinetic traces providing raw data of the G4 opening reaction and the fitting model applied in every case. In addition CD spectra and UV melting data is also provided to confirm the stability of all the DNA structures considered (G-quadruplex and duplex DNA). |
| first_indexed | 2024-12-10T04:38:17Z |
| format | Article |
| id | doaj.art-30db6d9009b14af9bcb7cc1b95d27f2f |
| institution | Directory Open Access Journal |
| issn | 2352-3409 |
| language | English |
| last_indexed | 2024-12-10T04:38:17Z |
| publishDate | 2015-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Data in Brief |
| spelling | doaj.art-30db6d9009b14af9bcb7cc1b95d27f2f2022-12-22T02:01:56ZengElsevierData in Brief2352-34092015-12-015C82282810.1016/j.dib.2015.10.039Spectroscopic data for the G-quadruplex DNA to duplex DNA reactionOscar Mendoza0Juan Elezgaray1Jean-Louis Mergny2University of Bordeaux, 33600 Bordeaux, FranceUniversity of Bordeaux, 33600 Bordeaux, FranceUniversity of Bordeaux, 33600 Bordeaux, FranceThis article describes additional data related to a research article entitled “Kinetics of Quadruplex to Duplex Conversion” (Mendoza et al. 2015 [1]). We followed the opening reaction of a series of intramolecular G-quadruplex structures by the addition of their corresponding complementary strand. Fluorolabeled complementary strands allowed to monitor the reaction in real-time. An adapted kinetic model was then applied in order to obtain the kinetic parameters of this reaction. We present a series of kinetic traces providing raw data of the G4 opening reaction and the fitting model applied in every case. In addition CD spectra and UV melting data is also provided to confirm the stability of all the DNA structures considered (G-quadruplex and duplex DNA).http://www.sciencedirect.com/science/article/pii/S2352340915002875 |
| spellingShingle | Oscar Mendoza Juan Elezgaray Jean-Louis Mergny Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction Data in Brief |
| title | Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction |
| title_full | Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction |
| title_fullStr | Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction |
| title_full_unstemmed | Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction |
| title_short | Spectroscopic data for the G-quadruplex DNA to duplex DNA reaction |
| title_sort | spectroscopic data for the g quadruplex dna to duplex dna reaction |
| url | http://www.sciencedirect.com/science/article/pii/S2352340915002875 |
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