Nationwide Data on the Characteristics of Linked-to-Care Chronic Hepatitis B in Korea
Linkage-to-care rate of chronic hepatitis B (CHB) is less well characterized. We aimed to evaluate the proportion, characteristics of CHB patients who are linked to care. We retrospectively analyzed insurance reimbursement claims data provided by the Korean National Health Insurance Service. CHB pat...
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MDPI AG
2021-10-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/20/4633 |
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| author | Young Cheol Ju Dae Won Jun Eileen L. Yoon Sang Bong Ahn Yun Jin Kim Mindie H. Nguyen |
| author_facet | Young Cheol Ju Dae Won Jun Eileen L. Yoon Sang Bong Ahn Yun Jin Kim Mindie H. Nguyen |
| author_sort | Young Cheol Ju |
| collection | DOAJ |
| description | Linkage-to-care rate of chronic hepatitis B (CHB) is less well characterized. We aimed to evaluate the proportion, characteristics of CHB patients who are linked to care. We retrospectively analyzed insurance reimbursement claims data provided by the Korean National Health Insurance Service. CHB patients who had at least two clinic or hospital visits that were associated with a CHB diagnostic code during 2002–2006 were included. Those without a history of malignancy at baseline were followed up until 2018. Mean follow-up period was 14.5 ± 2.9 years. Among the participants, 553,085 patients (35.8%) were found to be linked to care. The rates were lower in men than women (35.7% vs. 36.0%, <i>p</i> = 0.006). By age, it was highest for the 40′s age group at 44.8% and lowest at 29.4% for the 20′s age group (All <i>p</i> < 0.0001). The linkage-to-care rate was higher in rural area than metropolitan area (<i>p</i> < 0.0001). The 15-year cumulative incidence of hepatocellular carcinoma and overall survival rates among linked-to-care CHB patients were 18.2% and 93.8%, respectively. Two thirds of CHB patients were not linked to care. Those who are male, dwelling in metropolitan areas, and not in life transition periods need to be targeted to improve the linkage-to-care rate in Korea. |
| first_indexed | 2024-03-10T06:28:40Z |
| format | Article |
| id | doaj.art-30dbea35542945a7b0331c51c02ddf8b |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T06:28:40Z |
| publishDate | 2021-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-30dbea35542945a7b0331c51c02ddf8b2023-11-22T18:40:44ZengMDPI AGJournal of Clinical Medicine2077-03832021-10-011020463310.3390/jcm10204633Nationwide Data on the Characteristics of Linked-to-Care Chronic Hepatitis B in KoreaYoung Cheol Ju0Dae Won Jun1Eileen L. Yoon2Sang Bong Ahn3Yun Jin Kim4Mindie H. Nguyen5Department of Translational Medicine, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, KoreaDepartment of Translational Medicine, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, KoreaDepartment of Internal Medicine, Hanyang University Hospital, Hanyang University College of Medicine, Seoul 04763, KoreaNowon Eulji Medical Center, Department of Internal Medicine, Eulji University College of Medicine, Seoul 01830, KoreaBiostatistical Consulting and Research Laboratory, Medical Research Collaborating Center, Hanyang University, Seoul 04763, KoreaDivision of Gastroenterology and Hepatology, Stanford University Medical Center, Palo Alto, CA 94305, USALinkage-to-care rate of chronic hepatitis B (CHB) is less well characterized. We aimed to evaluate the proportion, characteristics of CHB patients who are linked to care. We retrospectively analyzed insurance reimbursement claims data provided by the Korean National Health Insurance Service. CHB patients who had at least two clinic or hospital visits that were associated with a CHB diagnostic code during 2002–2006 were included. Those without a history of malignancy at baseline were followed up until 2018. Mean follow-up period was 14.5 ± 2.9 years. Among the participants, 553,085 patients (35.8%) were found to be linked to care. The rates were lower in men than women (35.7% vs. 36.0%, <i>p</i> = 0.006). By age, it was highest for the 40′s age group at 44.8% and lowest at 29.4% for the 20′s age group (All <i>p</i> < 0.0001). The linkage-to-care rate was higher in rural area than metropolitan area (<i>p</i> < 0.0001). The 15-year cumulative incidence of hepatocellular carcinoma and overall survival rates among linked-to-care CHB patients were 18.2% and 93.8%, respectively. Two thirds of CHB patients were not linked to care. Those who are male, dwelling in metropolitan areas, and not in life transition periods need to be targeted to improve the linkage-to-care rate in Korea.https://www.mdpi.com/2077-0383/10/20/4633chronic hepatitis Bpublic healthdelivery of health carediagnosis ratehepatocellular carcinoma |
| spellingShingle | Young Cheol Ju Dae Won Jun Eileen L. Yoon Sang Bong Ahn Yun Jin Kim Mindie H. Nguyen Nationwide Data on the Characteristics of Linked-to-Care Chronic Hepatitis B in Korea Journal of Clinical Medicine chronic hepatitis B public health delivery of health care diagnosis rate hepatocellular carcinoma |
| title | Nationwide Data on the Characteristics of Linked-to-Care Chronic Hepatitis B in Korea |
| title_full | Nationwide Data on the Characteristics of Linked-to-Care Chronic Hepatitis B in Korea |
| title_fullStr | Nationwide Data on the Characteristics of Linked-to-Care Chronic Hepatitis B in Korea |
| title_full_unstemmed | Nationwide Data on the Characteristics of Linked-to-Care Chronic Hepatitis B in Korea |
| title_short | Nationwide Data on the Characteristics of Linked-to-Care Chronic Hepatitis B in Korea |
| title_sort | nationwide data on the characteristics of linked to care chronic hepatitis b in korea |
| topic | chronic hepatitis B public health delivery of health care diagnosis rate hepatocellular carcinoma |
| url | https://www.mdpi.com/2077-0383/10/20/4633 |
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