Diverse and Abundant Multi-Drug Resistant E. coli in Matang Mangrove Estuaries, Malaysia
E. coli, an important vector distributing antimicrobial resistance in the environment, was found to be multi-drug resistant, abundant and genetically diverse in the Matang mangrove estuaries, Malaysia. One-third (34%) of the estuarine E. coli was multi-drug resistant. The highest antibiotic resistan...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-09-01
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| Series: | Frontiers in Microbiology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00977/full |
| _version_ | 1819224947277430784 |
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| author | Aziz eGhaderpour Aziz eGhaderpour Wing Sze eHo Li Lee eChew Li Lee eChew Chui Wei eBong Chui Wei eBong Ving Ching eChong Ving Ching eChong Kwai-Lin eThong Lay Ching eChai Lay Ching eChai |
| author_facet | Aziz eGhaderpour Aziz eGhaderpour Wing Sze eHo Li Lee eChew Li Lee eChew Chui Wei eBong Chui Wei eBong Ving Ching eChong Ving Ching eChong Kwai-Lin eThong Lay Ching eChai Lay Ching eChai |
| author_sort | Aziz eGhaderpour |
| collection | DOAJ |
| description | E. coli, an important vector distributing antimicrobial resistance in the environment, was found to be multi-drug resistant, abundant and genetically diverse in the Matang mangrove estuaries, Malaysia. One-third (34%) of the estuarine E. coli was multi-drug resistant. The highest antibiotic resistance prevalence was observed for aminoglycosides (83%) and beta-lactams (37%). Phylogenetic groups A and B1, being the most predominant E. coli, demonstrated the highest antibiotic resistant level and prevalence of integrons (integron I, 21%; integron II, 3%). Detection of phylogenetic group B23 downstream of fishing villages indicates human fecal contamination as a source of E. coli pollution. Enteroaggregative E. coli (1%) were also detected immediately downstream of the fishing village. The results indicated multi-drug resistance among E. coli circulating in Matang estuaries, which could be reflective of anthropogenic activities and aggravated by bacterial and antibiotic discharges from village lack of a sewerage system, aquaculture farms and upstream animal husbandry. |
| first_indexed | 2024-12-23T10:01:47Z |
| format | Article |
| id | doaj.art-30df5705d3534f30966cd0f7902b2f78 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-23T10:01:47Z |
| publishDate | 2015-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-30df5705d3534f30966cd0f7902b2f782022-12-21T17:51:11ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2015-09-01610.3389/fmicb.2015.00977147359Diverse and Abundant Multi-Drug Resistant E. coli in Matang Mangrove Estuaries, MalaysiaAziz eGhaderpour0Aziz eGhaderpour1Wing Sze eHo2Li Lee eChew3Li Lee eChew4Chui Wei eBong5Chui Wei eBong6Ving Ching eChong7Ving Ching eChong8Kwai-Lin eThong9Lay Ching eChai10Lay Ching eChai11University of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaUniversity of MalayaE. coli, an important vector distributing antimicrobial resistance in the environment, was found to be multi-drug resistant, abundant and genetically diverse in the Matang mangrove estuaries, Malaysia. One-third (34%) of the estuarine E. coli was multi-drug resistant. The highest antibiotic resistance prevalence was observed for aminoglycosides (83%) and beta-lactams (37%). Phylogenetic groups A and B1, being the most predominant E. coli, demonstrated the highest antibiotic resistant level and prevalence of integrons (integron I, 21%; integron II, 3%). Detection of phylogenetic group B23 downstream of fishing villages indicates human fecal contamination as a source of E. coli pollution. Enteroaggregative E. coli (1%) were also detected immediately downstream of the fishing village. The results indicated multi-drug resistance among E. coli circulating in Matang estuaries, which could be reflective of anthropogenic activities and aggravated by bacterial and antibiotic discharges from village lack of a sewerage system, aquaculture farms and upstream animal husbandry.http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00977/fullantibiotic resistanceE. coliphylogenetic groupsEAECMatang mangrove estuaries |
| spellingShingle | Aziz eGhaderpour Aziz eGhaderpour Wing Sze eHo Li Lee eChew Li Lee eChew Chui Wei eBong Chui Wei eBong Ving Ching eChong Ving Ching eChong Kwai-Lin eThong Lay Ching eChai Lay Ching eChai Diverse and Abundant Multi-Drug Resistant E. coli in Matang Mangrove Estuaries, Malaysia Frontiers in Microbiology antibiotic resistance E. coli phylogenetic groups EAEC Matang mangrove estuaries |
| title | Diverse and Abundant Multi-Drug Resistant E. coli in Matang Mangrove Estuaries, Malaysia |
| title_full | Diverse and Abundant Multi-Drug Resistant E. coli in Matang Mangrove Estuaries, Malaysia |
| title_fullStr | Diverse and Abundant Multi-Drug Resistant E. coli in Matang Mangrove Estuaries, Malaysia |
| title_full_unstemmed | Diverse and Abundant Multi-Drug Resistant E. coli in Matang Mangrove Estuaries, Malaysia |
| title_short | Diverse and Abundant Multi-Drug Resistant E. coli in Matang Mangrove Estuaries, Malaysia |
| title_sort | diverse and abundant multi drug resistant e coli in matang mangrove estuaries malaysia |
| topic | antibiotic resistance E. coli phylogenetic groups EAEC Matang mangrove estuaries |
| url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00977/full |
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