Testudines as Sentinels for Monitoring the Dissemination of Antibiotic Resistance in Marine Environments: An Integrative Review
Dissemination of antibiotic resistance (AR) in marine environments is a global concern with a propensity to affect public health and many ecosystems worldwide. We evaluated the use of sea turtles as sentinel species for monitoring AR in marine environments. In this field, antibiotic-resistant bacter...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/10/7/775 |
| _version_ | 1827688705143341056 |
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| author | Kezia Drane Roger Huerlimann Michelle Power Anna Whelan Ellen Ariel Madoc Sheehan Robert Kinobe |
| author_facet | Kezia Drane Roger Huerlimann Michelle Power Anna Whelan Ellen Ariel Madoc Sheehan Robert Kinobe |
| author_sort | Kezia Drane |
| collection | DOAJ |
| description | Dissemination of antibiotic resistance (AR) in marine environments is a global concern with a propensity to affect public health and many ecosystems worldwide. We evaluated the use of sea turtles as sentinel species for monitoring AR in marine environments. In this field, antibiotic-resistant bacteria have been commonly identified by using standard culture and sensitivity tests, leading to an overrepresentation of specific, culturable bacterial classes in the available literature. AR was detected against all major antibiotic classes, but the highest cumulative global frequency of resistance in all represented geographical sites was against the beta-lactam class by a two-fold difference compared to all other antibiotics. Wastewater facilities and turtle rehabilitation centres were associated with higher incidences of multidrug-resistant bacteria (MDRB) accounting for an average of 58% and 49% of resistant isolates, respectively. Furthermore, a relatively similar prevalence of MDRB was seen in all studied locations. These data suggest that anthropogenically driven selection pressures for the development of AR in sea turtles and marine environments are relatively similar worldwide. There is a need, however, to establish direct demonstrable associations between AR in sea turtles in their respective marine environments with wastewater facilities and other anthropogenic activities worldwide. |
| first_indexed | 2024-03-10T10:03:22Z |
| format | Article |
| id | doaj.art-30df9148cbcc468db911ef577eb96e40 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-10T10:03:22Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-30df9148cbcc468db911ef577eb96e402023-11-22T01:45:35ZengMDPI AGAntibiotics2079-63822021-06-0110777510.3390/antibiotics10070775Testudines as Sentinels for Monitoring the Dissemination of Antibiotic Resistance in Marine Environments: An Integrative ReviewKezia Drane0Roger Huerlimann1Michelle Power2Anna Whelan3Ellen Ariel4Madoc Sheehan5Robert Kinobe6Centre for Molecular Therapeutics, College of Public Health, Medical and Veterinary Sciences, Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD 4811, AustraliaCentre for Sustainable Tropical Fisheries and Aquaculture, Centre for Tropical Bioinformatics and Molecular Biology, College of Science and Engineering, James Cook University, Townsville, QLD 4811, AustraliaDepartment of Biological Sciences, Macquarie University, Sydney, NSW 2109, AustraliaTownsville Water and Waste, Wastewater Operations, Townsville, QLD 4810, AustraliaCentre for Molecular Therapeutics, College of Public Health, Medical and Veterinary Sciences, Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD 4811, AustraliaCollege of Science, Technology and Engineering, James Cook University, Townsville, QLD 4811, AustraliaCentre for Molecular Therapeutics, College of Public Health, Medical and Veterinary Sciences, Australian Institute of Tropical Health and Medicine, James Cook University, Townsville, QLD 4811, AustraliaDissemination of antibiotic resistance (AR) in marine environments is a global concern with a propensity to affect public health and many ecosystems worldwide. We evaluated the use of sea turtles as sentinel species for monitoring AR in marine environments. In this field, antibiotic-resistant bacteria have been commonly identified by using standard culture and sensitivity tests, leading to an overrepresentation of specific, culturable bacterial classes in the available literature. AR was detected against all major antibiotic classes, but the highest cumulative global frequency of resistance in all represented geographical sites was against the beta-lactam class by a two-fold difference compared to all other antibiotics. Wastewater facilities and turtle rehabilitation centres were associated with higher incidences of multidrug-resistant bacteria (MDRB) accounting for an average of 58% and 49% of resistant isolates, respectively. Furthermore, a relatively similar prevalence of MDRB was seen in all studied locations. These data suggest that anthropogenically driven selection pressures for the development of AR in sea turtles and marine environments are relatively similar worldwide. There is a need, however, to establish direct demonstrable associations between AR in sea turtles in their respective marine environments with wastewater facilities and other anthropogenic activities worldwide.https://www.mdpi.com/2079-6382/10/7/775anthropogenic pollutionantimicrobial pollutionmultidrug-resistant bacteriahorizontal gene transferwastewater treatment plantsturtle rehabilitation centres |
| spellingShingle | Kezia Drane Roger Huerlimann Michelle Power Anna Whelan Ellen Ariel Madoc Sheehan Robert Kinobe Testudines as Sentinels for Monitoring the Dissemination of Antibiotic Resistance in Marine Environments: An Integrative Review Antibiotics anthropogenic pollution antimicrobial pollution multidrug-resistant bacteria horizontal gene transfer wastewater treatment plants turtle rehabilitation centres |
| title | Testudines as Sentinels for Monitoring the Dissemination of Antibiotic Resistance in Marine Environments: An Integrative Review |
| title_full | Testudines as Sentinels for Monitoring the Dissemination of Antibiotic Resistance in Marine Environments: An Integrative Review |
| title_fullStr | Testudines as Sentinels for Monitoring the Dissemination of Antibiotic Resistance in Marine Environments: An Integrative Review |
| title_full_unstemmed | Testudines as Sentinels for Monitoring the Dissemination of Antibiotic Resistance in Marine Environments: An Integrative Review |
| title_short | Testudines as Sentinels for Monitoring the Dissemination of Antibiotic Resistance in Marine Environments: An Integrative Review |
| title_sort | testudines as sentinels for monitoring the dissemination of antibiotic resistance in marine environments an integrative review |
| topic | anthropogenic pollution antimicrobial pollution multidrug-resistant bacteria horizontal gene transfer wastewater treatment plants turtle rehabilitation centres |
| url | https://www.mdpi.com/2079-6382/10/7/775 |
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