Increased mortality from acute liver failure in Mexico

Introduction. There is significant geographic variation in the etiology and prognosis of acute liver failure (ALF). Since, little information is available for Latin America. We analyzed ALF mortality trends in Mexico.Material and methods. The rates of mortality attributable to ALF were obtained for...

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Main Authors: Norberto C. Chávez-Tapia, Tonatiuh Barrientos-Gutiérrez, Carlos Manuel Guerrero-López, Jean Josue Santiago-Hernández, Nahum Méndez-Sánchez, Misael Uribe
פורמט: Article
שפה:English
יצא לאור: Elsevier 2012-03-01
סדרה:Annals of Hepatology
נושאים:
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S1665268119310324
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author Norberto C. Chávez-Tapia
Tonatiuh Barrientos-Gutiérrez
Carlos Manuel Guerrero-López
Jean Josue Santiago-Hernández
Nahum Méndez-Sánchez
Misael Uribe
author_facet Norberto C. Chávez-Tapia
Tonatiuh Barrientos-Gutiérrez
Carlos Manuel Guerrero-López
Jean Josue Santiago-Hernández
Nahum Méndez-Sánchez
Misael Uribe
author_sort Norberto C. Chávez-Tapia
collection DOAJ
description Introduction. There is significant geographic variation in the etiology and prognosis of acute liver failure (ALF). Since, little information is available for Latin America. We analyzed ALF mortality trends in Mexico.Material and methods. The rates of mortality attributable to ALF were obtained for 1998 to 2009 from the National System of Health Information in Mexico and analyzed according to date, etiology, sex, age and geographic characteristics through graphical assessment and joinpoint regression.Results. From 1998 to 2009, 2,193 ALF-related deaths were reported. A threefold increase in ALF mortality was observed during the period from 1998 to 2009 (the global mortality rate increased from 13.1 to 40.2 deaths per 10,000,000 inhabitants). The most significant increase was observed for viral etiologies after 2006, affecting people 45 years old and over.Conclusion. ALF-related deaths have increased since 2006. Although we cannot speculate on the specific causes of this increase, it may reflect improvements in the access of vulnerable populations to health care.
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spelling doaj.art-30e63a95f8c3436f86cbceb68f1d9d4f2022-12-21T21:59:16ZengElsevierAnnals of Hepatology1665-26812012-03-01112257262Increased mortality from acute liver failure in MexicoNorberto C. Chávez-Tapia0Tonatiuh Barrientos-Gutiérrez1Carlos Manuel Guerrero-López2Jean Josue Santiago-Hernández3Nahum Méndez-Sánchez4Misael Uribe5Obesity and Digestive Diseases Unit, Medica Sur Clinic and Foundation, Mexico City, Mexico; Correspondence and reprint request:Center for Integrative Approaches to Health Disparities, University of Michigan; National Institute of Public Health, Mexico City, MexicoNational Institute of Public Health, Mexico City, MexicoObesity and Digestive Diseases Unit, Medica Sur Clinic and Foundation, Mexico City, MexicoObesity and Digestive Diseases Unit, Medica Sur Clinic and Foundation, Mexico City, MexicoObesity and Digestive Diseases Unit, Medica Sur Clinic and Foundation, Mexico City, MexicoIntroduction. There is significant geographic variation in the etiology and prognosis of acute liver failure (ALF). Since, little information is available for Latin America. We analyzed ALF mortality trends in Mexico.Material and methods. The rates of mortality attributable to ALF were obtained for 1998 to 2009 from the National System of Health Information in Mexico and analyzed according to date, etiology, sex, age and geographic characteristics through graphical assessment and joinpoint regression.Results. From 1998 to 2009, 2,193 ALF-related deaths were reported. A threefold increase in ALF mortality was observed during the period from 1998 to 2009 (the global mortality rate increased from 13.1 to 40.2 deaths per 10,000,000 inhabitants). The most significant increase was observed for viral etiologies after 2006, affecting people 45 years old and over.Conclusion. ALF-related deaths have increased since 2006. Although we cannot speculate on the specific causes of this increase, it may reflect improvements in the access of vulnerable populations to health care.http://www.sciencedirect.com/science/article/pii/S1665268119310324Fulminant liver failureHepatitisEpidemiology
spellingShingle Norberto C. Chávez-Tapia
Tonatiuh Barrientos-Gutiérrez
Carlos Manuel Guerrero-López
Jean Josue Santiago-Hernández
Nahum Méndez-Sánchez
Misael Uribe
Increased mortality from acute liver failure in Mexico
Annals of Hepatology
Fulminant liver failure
Hepatitis
Epidemiology
title Increased mortality from acute liver failure in Mexico
title_full Increased mortality from acute liver failure in Mexico
title_fullStr Increased mortality from acute liver failure in Mexico
title_full_unstemmed Increased mortality from acute liver failure in Mexico
title_short Increased mortality from acute liver failure in Mexico
title_sort increased mortality from acute liver failure in mexico
topic Fulminant liver failure
Hepatitis
Epidemiology
url http://www.sciencedirect.com/science/article/pii/S1665268119310324
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AT jeanjosuesantiagohernandez increasedmortalityfromacuteliverfailureinmexico
AT nahummendezsanchez increasedmortalityfromacuteliverfailureinmexico
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