Initial joint bleed volume in a delayed on‐demand treatment setup correlates with subsequent synovial changes in hemophilic mice

Initial joint bleed volume in a delayed on‐demand treatment setup correlates with subsequent synovial changes in hemophilic mice

Abstract Background Hemophilic arthropathy is a debilitating morbidity of hemophilia caused by recurrent joint bleeds. We investigated if the joint bleed volume, before initiation of treatment, was linked to the subsequent degree of histopathological changes and the development of bone pathology in...

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Bibliographic Details
Main Authors: Kåre Kryger Vøls, Mads Kjelgaard‐Hansen, Carsten Dan Ley, Axel Kornerup Hansen, Maj Petersen
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:Animal Models and Experimental Medicine
Subjects:
Animal models
arthropathy
hemarthrosis
haemophilia A
in vivo imaging
micro‐CT
Online Access:https://doi.org/10.1002/ame2.12118

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