Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism
A 6-month-old kitten, male, domestic shorthair cat was presented with dwarfism, ocular and nasal discharge, and Ascaris infestation. Congenital hyposomatotropism was diagnosed on the basis of serum level of insulin-like growth factor-1 (IGF-I). The cat was treated with human recombinant growth hormo...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-11-01
|
| Series: | Frontiers in Veterinary Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fvets.2021.773355/full |
| _version_ | 1819006498923085824 |
|---|---|
| author | Martina Načeradská Martina Načeradská Kateřina Návojová Horáčková Michaela Fridrichová |
| author_facet | Martina Načeradská Martina Načeradská Kateřina Návojová Horáčková Michaela Fridrichová |
| author_sort | Martina Načeradská |
| collection | DOAJ |
| description | A 6-month-old kitten, male, domestic shorthair cat was presented with dwarfism, ocular and nasal discharge, and Ascaris infestation. Congenital hyposomatotropism was diagnosed on the basis of serum level of insulin-like growth factor-1 (IGF-I). The cat was treated with human recombinant growth hormone for 9 weeks. After that, his liver enzymes became elevated, and the therapy was discontinued. His IGF-I levels were normal at the end of the therapy. Normal IGF-I was present 3 months after discontinuation of therapy with human recombinant growth hormone and even half a year after the discontinuation. All other comorbidities were addressed with the therapy. The cat is now the size of normal cats, living with the first author. |
| first_indexed | 2024-12-21T00:09:39Z |
| format | Article |
| id | doaj.art-30eec9f265384961bb508d603d5d1869 |
| institution | Directory Open Access Journal |
| issn | 2297-1769 |
| language | English |
| last_indexed | 2024-12-21T00:09:39Z |
| publishDate | 2021-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Veterinary Science |
| spelling | doaj.art-30eec9f265384961bb508d603d5d18692022-12-21T19:22:23ZengFrontiers Media S.A.Frontiers in Veterinary Science2297-17692021-11-01810.3389/fvets.2021.773355773355Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With DwarfismMartina Načeradská0Martina Načeradská1Kateřina Návojová Horáčková2Michaela Fridrichová3Department of Veterinary Sciences, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences in Prague, Prague, CzechiaVeterinární ordinace MVDr. Martiny Načeradské, Prague, CzechiaVeterinární ordinace U stříbrné kočičky, Prague, CzechiaDepartment of Inorganic Chemistry, Faculty of Science, Charles University, Prague, CzechiaA 6-month-old kitten, male, domestic shorthair cat was presented with dwarfism, ocular and nasal discharge, and Ascaris infestation. Congenital hyposomatotropism was diagnosed on the basis of serum level of insulin-like growth factor-1 (IGF-I). The cat was treated with human recombinant growth hormone for 9 weeks. After that, his liver enzymes became elevated, and the therapy was discontinued. His IGF-I levels were normal at the end of the therapy. Normal IGF-I was present 3 months after discontinuation of therapy with human recombinant growth hormone and even half a year after the discontinuation. All other comorbidities were addressed with the therapy. The cat is now the size of normal cats, living with the first author.https://www.frontiersin.org/articles/10.3389/fvets.2021.773355/fulldwarfismhuman growth hormonecathyposomatotropismIGF-I |
| spellingShingle | Martina Načeradská Martina Načeradská Kateřina Návojová Horáčková Michaela Fridrichová Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism Frontiers in Veterinary Science dwarfism human growth hormone cat hyposomatotropism IGF-I |
| title | Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism |
| title_full | Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism |
| title_fullStr | Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism |
| title_full_unstemmed | Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism |
| title_short | Case Report: Human Recombinant Growth Hormone Therapy in a DSH Cat Presented With Dwarfism |
| title_sort | case report human recombinant growth hormone therapy in a dsh cat presented with dwarfism |
| topic | dwarfism human growth hormone cat hyposomatotropism IGF-I |
| url | https://www.frontiersin.org/articles/10.3389/fvets.2021.773355/full |
| work_keys_str_mv | AT martinanaceradska casereporthumanrecombinantgrowthhormonetherapyinadshcatpresentedwithdwarfism AT martinanaceradska casereporthumanrecombinantgrowthhormonetherapyinadshcatpresentedwithdwarfism AT katerinanavojovahorackova casereporthumanrecombinantgrowthhormonetherapyinadshcatpresentedwithdwarfism AT michaelafridrichova casereporthumanrecombinantgrowthhormonetherapyinadshcatpresentedwithdwarfism |