Anti-Invasive and Anti-Migratory Effects of Ononin on Human Osteosarcoma Cells by Limiting the MMP2/9 and EGFR-Erk1/2 Pathway

Anti-Invasive and Anti-Migratory Effects of Ononin on Human Osteosarcoma Cells by Limiting the MMP2/9 and EGFR-Erk1/2 Pathway

Osteosarcoma is a common malignancy of the bone. Due to its high metastatic properties, osteosarcoma becomes the leading cause of cancer death worldwide. Ononin is an isoflavone glycoside known to have various pharmacological properties, including antioxidant and anti-inflammatory activities. In the...

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Bibliographic Details
Main Authors: Guowei Gong, Kumar Ganesan, Qingping Xiong, Yuzhong Zheng
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
ononin
invasion
migration
osteosarcoma
inhibitory effects
Online Access:https://www.mdpi.com/2072-6694/15/3/758

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