Diffusion through permeable interfaces: Fundamental equations and their application to first-passage and local time statistics

The diffusion equation is the primary tool to study the movement dynamics of a free Brownian particle, but when spatial heterogeneities in the form of permeable interfaces are present, no fundamental equation has been derived. Here we obtain such an equation from a microscopic description using a la...

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Bibliographic Details
Main Authors: Toby Kay, Luca Giuggioli
Format: Article
Language:English
Published: American Physical Society 2022-09-01
Series:Physical Review Research
Online Access:http://doi.org/10.1103/PhysRevResearch.4.L032039
Description
Summary:The diffusion equation is the primary tool to study the movement dynamics of a free Brownian particle, but when spatial heterogeneities in the form of permeable interfaces are present, no fundamental equation has been derived. Here we obtain such an equation from a microscopic description using a lattice random walk model. The sought after Fokker-Planck description and the corresponding backward Kolmogorov equation are employed to investigate first-passage and local time statistics and gain new insights. Among them a surprising phenomenon, in the case of a semibounded domain, is the appearance of a regime of dependence and independence on the location of the permeable barrier in the mean first-passage time. The new formalism is completely general: it allows to study the dynamics in the presence of multiple permeable barriers as well as reactive heterogeneities in bounded or unbounded domains and under the influence of external forces.
ISSN:2643-1564