Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat
Objective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression. In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac t...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2016-08-01
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| Series: | Iranian Journal of Basic Medical Sciences |
| Subjects: | |
| Online Access: | http://ijbms.mums.ac.ir/article_7462_a245c794b6940b8b4a8333dd5a6c7879.pdf |
| _version_ | 1818059588472143872 |
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| author | Danka Đevenica Anita Markotić Nikolina Režić-Mužinić Igor Jelaska Tatijana Zemunik Hrvoje Delić Vedrana Čikeš Čulić |
| author_facet | Danka Đevenica Anita Markotić Nikolina Režić-Mužinić Igor Jelaska Tatijana Zemunik Hrvoje Delić Vedrana Čikeš Čulić |
| author_sort | Danka Đevenica |
| collection | DOAJ |
| description | Objective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression. In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. Materials and Methods:Expression of CD11b and CD15s on leukocytes, as well as CD77 and CD34 expression on endothelial cells in cell suspensions of renal, pulmonary and cardiac tissue in rats after hyperbaric treatment and in control rats were determined by flow cytometry. Results: Hyperbaric treatment significantly increased percentage of leukocytes expressing CD15s+CD11b- (from 1.71±1.11 to 23.42±2.85, P |
| first_indexed | 2024-12-10T13:18:55Z |
| format | Article |
| id | doaj.art-30f8375f6baa46cc82cfb8ec575b059a |
| institution | Directory Open Access Journal |
| issn | 2008-3866 2008-3874 |
| language | English |
| last_indexed | 2024-12-10T13:18:55Z |
| publishDate | 2016-08-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Basic Medical Sciences |
| spelling | doaj.art-30f8375f6baa46cc82cfb8ec575b059a2022-12-22T01:47:25ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742016-08-0119882182810.22038/ijbms.2016.74627462Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in ratDanka Đevenica0Anita Markotić1Nikolina Režić-Mužinić2Igor Jelaska3Tatijana Zemunik4Hrvoje Delić5Vedrana Čikeš Čulić6Postgraduate Student at University of Split School of Medicine, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaFaculty of Kinesiology, University of Split, Split, CroatiaDepartment of Medical Biology, University of Split School of Medicine, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaDepartment of Medical Chemistry and Biochemistry, University of Split School of Medicine, Split, CroatiaObjective(s): The aim of this study was to estimate effects of hyperbaric (HB) treatment by determination of CD15s and CD11b leukocyte proinflammatory markers expression. In addition, this study describes changes in CD77 and CD34 expression on rat endothelial cells in renal, pulmonary and cardiac tissue following exposure to hyperbaric pressure. Materials and Methods:Expression of CD11b and CD15s on leukocytes, as well as CD77 and CD34 expression on endothelial cells in cell suspensions of renal, pulmonary and cardiac tissue in rats after hyperbaric treatment and in control rats were determined by flow cytometry. Results: Hyperbaric treatment significantly increased percentage of leukocytes expressing CD15s+CD11b- (from 1.71±1.11 to 23.42±2.85, Phttp://ijbms.mums.ac.ir/article_7462_a245c794b6940b8b4a8333dd5a6c7879.pdfCD15s(sialyl Lexis X antigen)CD77(globotriaosylceramide)CD34 antigenEnvironment |
| spellingShingle | Danka Đevenica Anita Markotić Nikolina Režić-Mužinić Igor Jelaska Tatijana Zemunik Hrvoje Delić Vedrana Čikeš Čulić Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat Iranian Journal of Basic Medical Sciences CD15s(sialyl Lexis X antigen) CD77(globotriaosylceramide) CD34 antigen Environment |
| title | Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat |
| title_full | Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat |
| title_fullStr | Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat |
| title_full_unstemmed | Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat |
| title_short | Hyperbaric environment up-regulates CD15s expression on leukocytes, down-regulates CD77 expression on renal cells and up-regulates CD34 expression on pulmonary and cardiac cells in rat |
| title_sort | hyperbaric environment up regulates cd15s expression on leukocytes down regulates cd77 expression on renal cells and up regulates cd34 expression on pulmonary and cardiac cells in rat |
| topic | CD15s(sialyl Lexis X antigen) CD77(globotriaosylceramide) CD34 antigen Environment |
| url | http://ijbms.mums.ac.ir/article_7462_a245c794b6940b8b4a8333dd5a6c7879.pdf |
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