Induced protection from a CCHFV-M DNA vaccine requires CD8+ T cells

Induced protection from a CCHFV-M DNA vaccine requires CD8+ T cells

Crimean-Congo hemorrhagic fever (CCHF) is a World Health Organization prioritized disease because its broad distribution and severity of disease make it a global health threat. Despite advancements in preclinical vaccine development for CCHF virus (CCHFV), including multiple platforms targeting mult...

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Bibliographic Details
Main Authors: Joseph W. Golden, Collin J. Fitzpatrick, John J. Suschak, Tamara L. Clements, Keersten M. Ricks, Mariano Sanchez-Lockhart, Aura R. Garrison
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Virus Research
Subjects:
Crimean-Congo hemorrhagic fever
Correlates of protection
CD8+ T cells
DNA vaccine
Glycoproteins
M-segment
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170223001351

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