Hypersensitivity to Intravenous Iron Preparations
Intravenous iron is widely used for the treatment of iron deficiency anemia when adherence to oral iron replacement is poor. Acute hypersensitivity reactions during iron infusions are very rare but can be life threatening. Major risk factors for hypersensitivity reactions include a previous reaction...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/9/10/1473 |
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| author | Silvia Caimmi Giuseppe Crisafulli Fabrizio Franceschini Lucia Liotti Annamaria Bianchi Paolo Bottau Francesca Mori Paolo Triggiano Claudia Paglialunga Francesca Saretta Arianna Giannetti Giampaolo Ricci Carlo Caffarelli |
| author_facet | Silvia Caimmi Giuseppe Crisafulli Fabrizio Franceschini Lucia Liotti Annamaria Bianchi Paolo Bottau Francesca Mori Paolo Triggiano Claudia Paglialunga Francesca Saretta Arianna Giannetti Giampaolo Ricci Carlo Caffarelli |
| author_sort | Silvia Caimmi |
| collection | DOAJ |
| description | Intravenous iron is widely used for the treatment of iron deficiency anemia when adherence to oral iron replacement is poor. Acute hypersensitivity reactions during iron infusions are very rare but can be life threatening. Major risk factors for hypersensitivity reactions include a previous reaction to an iron infusion, a fast iron infusion rate, multiple drug allergies, atopic diseases, high serum tryptase levels, asthma, and urticaria. The management of iron infusions requires meticulous observation, and, in the event of an adverse reaction, prompt recognition and severity-related interventions by well-trained medical and nursing staff. Avoidance of IV iron products in patients with iron hypersensitivity reactions may not be considered as a standard practice. |
| first_indexed | 2024-03-09T20:27:00Z |
| format | Article |
| id | doaj.art-30fcb25ff90244bd82761b2c7d0a0404 |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-09T20:27:00Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-30fcb25ff90244bd82761b2c7d0a04042023-11-23T23:31:32ZengMDPI AGChildren2227-90672022-09-01910147310.3390/children9101473Hypersensitivity to Intravenous Iron PreparationsSilvia Caimmi0Giuseppe Crisafulli1Fabrizio Franceschini2Lucia Liotti3Annamaria Bianchi4Paolo Bottau5Francesca Mori6Paolo Triggiano7Claudia Paglialunga8Francesca Saretta9Arianna Giannetti10Giampaolo Ricci11Carlo Caffarelli12UOC Pediatria, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, ItalyUOC Pediatria, Università di Messina, 98124 Messina, ItalyUOC Pediatria, Azienda Ospedaliero-Universitaria “Ospedali Riuniti”, 60020 Ancona, ItalyUOC Pediatria, Azienda Ospedaliero-Universitaria “Ospedali Riuniti”, 60020 Ancona, ItalyUOC Pediatria, Azienda Ospedaliera San Camillo Forlanini, 00152 Roma, ItalyDipartimento di Pediatria e Neonatologia, Ospedale di Imola, 40026 Imola, ItalyAllergy Unit, Meyer Children’s Hospital, 50139 Florence, ItalyUOC Pediatria, Fondazione IRCCS Policlinico San Matteo, 27100 Pavia, ItalyUOC di Pediatria, Azienda Ospedaliera-Universitaria “Consorziale-Policlinico”, Ospedale Pediatrico Giovanni XXIII, 70123 Bari, ItalySC Pediatria, Ospedale Latisana-Palmanova, Dipartimento Materno-Infantile Azienda Sanitaria Universitaria Friuli Centrale, 33100 Udine, ItalyPediatric Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, ItalyDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, ItalyClinica Pediatrica, Azienda Ospedaliero-Universitaria, Dipartimento Medicina e Chirurgia, Università di Parma, 43126 Parma, ItalyIntravenous iron is widely used for the treatment of iron deficiency anemia when adherence to oral iron replacement is poor. Acute hypersensitivity reactions during iron infusions are very rare but can be life threatening. Major risk factors for hypersensitivity reactions include a previous reaction to an iron infusion, a fast iron infusion rate, multiple drug allergies, atopic diseases, high serum tryptase levels, asthma, and urticaria. The management of iron infusions requires meticulous observation, and, in the event of an adverse reaction, prompt recognition and severity-related interventions by well-trained medical and nursing staff. Avoidance of IV iron products in patients with iron hypersensitivity reactions may not be considered as a standard practice.https://www.mdpi.com/2227-9067/9/10/1473ironiron hypersensitivitydesensitizationdrug allergyhypersensitivity reactiondrug provocation test |
| spellingShingle | Silvia Caimmi Giuseppe Crisafulli Fabrizio Franceschini Lucia Liotti Annamaria Bianchi Paolo Bottau Francesca Mori Paolo Triggiano Claudia Paglialunga Francesca Saretta Arianna Giannetti Giampaolo Ricci Carlo Caffarelli Hypersensitivity to Intravenous Iron Preparations Children iron iron hypersensitivity desensitization drug allergy hypersensitivity reaction drug provocation test |
| title | Hypersensitivity to Intravenous Iron Preparations |
| title_full | Hypersensitivity to Intravenous Iron Preparations |
| title_fullStr | Hypersensitivity to Intravenous Iron Preparations |
| title_full_unstemmed | Hypersensitivity to Intravenous Iron Preparations |
| title_short | Hypersensitivity to Intravenous Iron Preparations |
| title_sort | hypersensitivity to intravenous iron preparations |
| topic | iron iron hypersensitivity desensitization drug allergy hypersensitivity reaction drug provocation test |
| url | https://www.mdpi.com/2227-9067/9/10/1473 |
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