Calpain: the regulatory point of myocardial ischemia-reperfusion injury
Calpain is a conserved cysteine protease readily expressed in several mammalian tissues, which is usually activated by Ca2+ and with maximum activity at neutral pH. The activity of calpain is tightly regulated because its aberrant activation will nonspecifically cleave various proteins in cells. Abn...
Main Authors: | Guo-Yang Liu, Wan-Li Xie, Yan-Ting Wang, Lu Chen, Zhen-Zhen Xu, Yong Lv, Qing-Ping Wu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-06-01
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Series: | Frontiers in Cardiovascular Medicine |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1194402/full |
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