Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview
Endocrine disruptive chemicals (EDC) are known to alter thyroid function and have been associated with increased risk of certain cancers. The present study aims to provide a comprehensive overview of available studies on the association between EDC exposure and thyroid cancer. Relevant studies were...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | Toxics |
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| Online Access: | https://www.mdpi.com/2305-6304/9/1/14 |
| _version_ | 1797409936851861504 |
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| author | Mathilda Alsen Catherine Sinclair Peter Cooke Kimia Ziadkhanpour Eric Genden Maaike van Gerwen |
| author_facet | Mathilda Alsen Catherine Sinclair Peter Cooke Kimia Ziadkhanpour Eric Genden Maaike van Gerwen |
| author_sort | Mathilda Alsen |
| collection | DOAJ |
| description | Endocrine disruptive chemicals (EDC) are known to alter thyroid function and have been associated with increased risk of certain cancers. The present study aims to provide a comprehensive overview of available studies on the association between EDC exposure and thyroid cancer. Relevant studies were identified via a literature search in the National Library of Medicine and National Institutes of Health PubMed as well as a review of reference lists of all retrieved articles and of previously published relevant reviews. Overall, the current literature suggests that exposure to certain congeners of flame retardants, polychlorinated biphenyls (PCBs), and phthalates as well as certain pesticides may potentially be associated with an increased risk of thyroid cancer. However, future research is urgently needed to evaluate the different EDCs and their potential carcinogenic effect on the thyroid gland in humans as most EDCs have been studied sporadically and results are not consistent. |
| first_indexed | 2024-03-09T04:21:43Z |
| format | Article |
| id | doaj.art-30ff7581cfa24a30884f1148dcad1d16 |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-03-09T04:21:43Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-30ff7581cfa24a30884f1148dcad1d162023-12-03T13:45:50ZengMDPI AGToxics2305-63042021-01-01911410.3390/toxics9010014Endocrine Disrupting Chemicals and Thyroid Cancer: An OverviewMathilda Alsen0Catherine Sinclair1Peter Cooke2Kimia Ziadkhanpour3Eric Genden4Maaike van Gerwen5Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USADepartment of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USADepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USADepartment of Medical Education, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USADepartment of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USADepartment of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USAEndocrine disruptive chemicals (EDC) are known to alter thyroid function and have been associated with increased risk of certain cancers. The present study aims to provide a comprehensive overview of available studies on the association between EDC exposure and thyroid cancer. Relevant studies were identified via a literature search in the National Library of Medicine and National Institutes of Health PubMed as well as a review of reference lists of all retrieved articles and of previously published relevant reviews. Overall, the current literature suggests that exposure to certain congeners of flame retardants, polychlorinated biphenyls (PCBs), and phthalates as well as certain pesticides may potentially be associated with an increased risk of thyroid cancer. However, future research is urgently needed to evaluate the different EDCs and their potential carcinogenic effect on the thyroid gland in humans as most EDCs have been studied sporadically and results are not consistent.https://www.mdpi.com/2305-6304/9/1/14endocrine disruptive chemicalsthyroid cancerpesticidesflame retardantspolychlorinated biphenylsphthalates |
| spellingShingle | Mathilda Alsen Catherine Sinclair Peter Cooke Kimia Ziadkhanpour Eric Genden Maaike van Gerwen Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview Toxics endocrine disruptive chemicals thyroid cancer pesticides flame retardants polychlorinated biphenyls phthalates |
| title | Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview |
| title_full | Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview |
| title_fullStr | Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview |
| title_full_unstemmed | Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview |
| title_short | Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview |
| title_sort | endocrine disrupting chemicals and thyroid cancer an overview |
| topic | endocrine disruptive chemicals thyroid cancer pesticides flame retardants polychlorinated biphenyls phthalates |
| url | https://www.mdpi.com/2305-6304/9/1/14 |
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