Transcriptomic analysis of neuregulin-1 regulated genes following ischemic stroke by computational identification of promoter binding sites: A role for the ETS-1 transcription factor.
Ischemic stroke is a major cause of mortality in the United States. We previously showed that neuregulin-1 (NRG1) was neuroprotective in rat models of ischemic stroke. We used gene expression profiling to understand the early cellular and molecular mechanisms of NRG1's effects after the inducti...
Main Authors: | Monique C Surles-Zeigler, Yonggang Li, Timothy J Distel, Hakeem Omotayo, Shaokui Ge, Byron D Ford |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5983438?pdf=render |
Similar Items
-
The case for neuregulin-1 as a clinical treatment for stroke
by: Jessica M. Noll, et al.
Published: (2024-04-01) -
Alteration of serum neuregulin 4 and neuregulin 1 in gestational diabetes mellitus
by: Lei Zhang, et al.
Published: (2021-10-01) -
Neuroprotection by neuregulin-1 following focal stroke is associated with the attenuation of ischemia-induced pro-inflammatory and stress gene expression
by: Zhenfeng Xu, et al.
Published: (2005-08-01) -
Regulation of NRG-1-ErbB4 signaling and neuroprotection by exogenous neuregulin-1 in a mouse model of epilepsy
by: Allison R. Peterson, et al.
Published: (2021-12-01) -
Neuregulin 1 genotype and schizophrenia.
by: Munafò, MR, et al.
Published: (2008)