Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial.
Evidence is accumulating that mindfulness training has favorable effects on psychological outcomes, but studies on physiological outcomes are limited. Patients with heart disease have a high incidence of physiological and psychological problems and may benefit from mindfulness training. Our aim was...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4671576?pdf=render |
| _version_ | 1828160398377877504 |
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| author | John O Younge Machteld F Wery Rinske A Gotink Elisabeth M W J Utens Michelle Michels Dimitris Rizopoulos Elisabeth F C van Rossum M G Myriam Hunink Jolien W Roos-Hesselink |
| author_facet | John O Younge Machteld F Wery Rinske A Gotink Elisabeth M W J Utens Michelle Michels Dimitris Rizopoulos Elisabeth F C van Rossum M G Myriam Hunink Jolien W Roos-Hesselink |
| author_sort | John O Younge |
| collection | DOAJ |
| description | Evidence is accumulating that mindfulness training has favorable effects on psychological outcomes, but studies on physiological outcomes are limited. Patients with heart disease have a high incidence of physiological and psychological problems and may benefit from mindfulness training. Our aim was to determine the beneficial physiological and psychological effects of online mindfulness training in patients with heart disease.The study was a pragmatic randomized controlled single-blind trial. Between June 2012 and April 2014 we randomized 324 patients (mean age 43.2 years, 53.7% male) with heart disease in a 2:1 ratio (n = 215 versus n = 109) to a 12-week online mindfulness training in addition to usual care (UC) compared to UC alone. The primary outcome was exercise capacity measured with the 6 minute walk test (6MWT). Secondary outcomes were other physiological parameters (heart rate, blood pressure, respiratory rate, and NT-proBNP), subjective health status (SF-36), perceived stress (PSS), psychological well-being (HADS), social support (PSSS12) and a composite endpoint (all-cause mortality, heart failure, symptomatic arrhythmia, cardiac surgery, and percutaneous cardiac intervention). Linear mixed models were used to evaluate differences between groups on the repeated outcome measures.Compared to UC, mindfulness showed a borderline significant improved 6MWT (effect size, meters: 13.2, 95%CI: -0.02; 26.4, p = 0.050). There was also a significant lower heart rate in favor of the mindfulness group (effect size, beats per minute: -2.8, 95%CI: -5.4;-0.2, p = 0.033). No significant differences were seen on other outcomes.Mindfulness training showed positive effects on the physiological parameters exercise capacity and heart rate and it might therefore be a useful adjunct to current clinical therapy in patients with heart disease.Dutch Trial Register 3453. |
| first_indexed | 2024-04-12T00:18:46Z |
| format | Article |
| id | doaj.art-3107532bad2544a584e2ca9bf906912f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T00:18:46Z |
| publishDate | 2015-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-3107532bad2544a584e2ca9bf906912f2022-12-22T03:55:46ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-011012e014384310.1371/journal.pone.0143843Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial.John O YoungeMachteld F WeryRinske A GotinkElisabeth M W J UtensMichelle MichelsDimitris RizopoulosElisabeth F C van RossumM G Myriam HuninkJolien W Roos-HesselinkEvidence is accumulating that mindfulness training has favorable effects on psychological outcomes, but studies on physiological outcomes are limited. Patients with heart disease have a high incidence of physiological and psychological problems and may benefit from mindfulness training. Our aim was to determine the beneficial physiological and psychological effects of online mindfulness training in patients with heart disease.The study was a pragmatic randomized controlled single-blind trial. Between June 2012 and April 2014 we randomized 324 patients (mean age 43.2 years, 53.7% male) with heart disease in a 2:1 ratio (n = 215 versus n = 109) to a 12-week online mindfulness training in addition to usual care (UC) compared to UC alone. The primary outcome was exercise capacity measured with the 6 minute walk test (6MWT). Secondary outcomes were other physiological parameters (heart rate, blood pressure, respiratory rate, and NT-proBNP), subjective health status (SF-36), perceived stress (PSS), psychological well-being (HADS), social support (PSSS12) and a composite endpoint (all-cause mortality, heart failure, symptomatic arrhythmia, cardiac surgery, and percutaneous cardiac intervention). Linear mixed models were used to evaluate differences between groups on the repeated outcome measures.Compared to UC, mindfulness showed a borderline significant improved 6MWT (effect size, meters: 13.2, 95%CI: -0.02; 26.4, p = 0.050). There was also a significant lower heart rate in favor of the mindfulness group (effect size, beats per minute: -2.8, 95%CI: -5.4;-0.2, p = 0.033). No significant differences were seen on other outcomes.Mindfulness training showed positive effects on the physiological parameters exercise capacity and heart rate and it might therefore be a useful adjunct to current clinical therapy in patients with heart disease.Dutch Trial Register 3453.http://europepmc.org/articles/PMC4671576?pdf=render |
| spellingShingle | John O Younge Machteld F Wery Rinske A Gotink Elisabeth M W J Utens Michelle Michels Dimitris Rizopoulos Elisabeth F C van Rossum M G Myriam Hunink Jolien W Roos-Hesselink Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial. PLoS ONE |
| title | Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial. |
| title_full | Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial. |
| title_fullStr | Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial. |
| title_full_unstemmed | Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial. |
| title_short | Web-Based Mindfulness Intervention in Heart Disease: A Randomized Controlled Trial. |
| title_sort | web based mindfulness intervention in heart disease a randomized controlled trial |
| url | http://europepmc.org/articles/PMC4671576?pdf=render |
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