Evaluation of the Immunogenicity in Mice Orally Immunized with Recombinant <i>Lactobacillus casei</i> Expressing Porcine Epidemic Diarrhea Virus S1 Protein

Evaluation of the Immunogenicity in Mice Orally Immunized with Recombinant <i>Lactobacillus casei</i> Expressing Porcine Epidemic Diarrhea Virus S1 Protein

Porcine epidemic diarrhea (PED), characterized by diarrhea, vomiting, and dehydration, is an acute enteric infectious disease of pigs. The disease is caused by porcine epidemic diarrhea virus (PEDV), which infects the intestinal mucosal surface. Therefore, mucosal immunization through the oral route...

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Bibliographic Details
Main Authors: Ya Xiao, Xiaona Wang, Yue Li, Fengsai Li, Haiyuan Zhao, Yilan Shao, Liu Zhang, Guojie Ding, Jiaxuan Li, Yanping Jiang, Wen Cui, Zhifu Shan, Han Zhou, Li Wang, Xinyuan Qiao, Lijie Tang, Yijing Li
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Viruses
Subjects:
PEDV S1 glycoprotein
recombinant <i>Lactobacillus</i>
mucosal immunity
oral vaccine
Online Access:https://www.mdpi.com/1999-4915/14/5/890

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