Evaluation of the Immunogenicity in Mice Orally Immunized with Recombinant <i>Lactobacillus casei</i> Expressing Porcine Epidemic Diarrhea Virus S1 Protein

Evaluation of the Immunogenicity in Mice Orally Immunized with Recombinant <i>Lactobacillus casei</i> Expressing Porcine Epidemic Diarrhea Virus S1 Protein

Porcine epidemic diarrhea (PED), characterized by diarrhea, vomiting, and dehydration, is an acute enteric infectious disease of pigs. The disease is caused by porcine epidemic diarrhea virus (PEDV), which infects the intestinal mucosal surface. Therefore, mucosal immunization through the oral route...

Full description

Bibliographic Details
Main Authors:	Ya Xiao, Xiaona Wang, Yue Li, Fengsai Li, Haiyuan Zhao, Yilan Shao, Liu Zhang, Guojie Ding, Jiaxuan Li, Yanping Jiang, Wen Cui, Zhifu Shan, Han Zhou, Li Wang, Xinyuan Qiao, Lijie Tang, Yijing Li
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Series:	Viruses
Subjects:	PEDV S1 glycoprotein recombinant <i>Lactobacillus</i> mucosal immunity oral vaccine
Online Access:	https://www.mdpi.com/1999-4915/14/5/890

Similar Items

Immunogenicity of Recombinant-Deficient <i>Lactobacillus casei</i> with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus
by: Fengsai Li, et al.
Published: (2021-09-01)

Immune Responses in Pregnant Sows Induced by Recombinant <i>Lactobacillus johnsonii</i> Expressing the COE Protein of Porcine Epidemic Diarrhea Virus Provide Protection for Piglets against PEDV Infection
by: Dianzhong Zheng, et al.
Published: (2021-12-01)

Systemic and Oral Immunogenicity of Porcine Epidemic Diarrhea Virus Antigen Fused to Poly-Fc of Immunoglobulin G and Expressed in ΔXT/FT Nicotiana benthamiana Plants
by: Nguyen-Quang-Duc Tien, et al.
Published: (2021-04-01)

IPEC-J2 Autophagy Induced by TLR4 and NSP6 Interactions Facilitate Porcine Epidemic Diarrhea Virus Replication
by: Haiyuan Zhao, et al.
Published: (2024-11-01)

Oral Immunization with <i>Lactobacillus casei</i> Expressing the Porcine Circovirus Type 2 Cap and LTB Induces Mucosal and Systemic Antibody Responses in Mice
by: Fengsai Li, et al.
Published: (2021-07-01)

The Oral Inactivated Porcine Epidemic Diarrhea Virus Presenting in the Intestine Induces Mucosal Immunity in Mice with Alginate–Chitosan Microcapsules
by: Ziliang Qin, et al.
Published: (2023-02-01)

The construction of recombinant Lactobacillus casei vaccine of PEDV and its immune responses in mice
by: Xiaowen Li, et al.
Published: (2021-05-01)

Astragalus polysaccharide enhances maternal mucosal immunity against PEDV
by: Jianli Tang, et al.
Published: (2024-12-01)

Correction: Li et al. Immunogenicity of Recombinant-Deficient <i>Lactobacillus casei</i> with Complementary Plasmid Expressing Alanine Racemase Gene and Core Neutralizing Epitope Antigen against Porcine Epidemic Diarrhea Virus. <i>Vaccines</i> 2021, <i>9</i>, 1084
by: Fengsai Li, et al.
Published: (2023-02-01)

Auxotrophic <i>Lactobacillus</i> Expressing Porcine Rotavirus VP4 Constructed Using CRISPR-Cas9D10A System Induces Effective Immunity in Mice
by: Hailin Zhang, et al.
Published: (2022-09-01)

Pathogenicity and immunogenicity of attenuated porcine epidemic diarrhea virus PC22A strain in conventional weaned pigs
by: Chun-Ming Lin, et al.
Published: (2019-01-01)

Immunogenicity of eGFP-Marked Recombinant Lactobacillus casei against Transmissible Gastroenteritis Virus and Porcine Epidemic Diarrhea Virus
by: Meiling Yu, et al.
Published: (2017-09-01)

Intranasally inoculated bacterium-like particles displaying porcine epidemic diarrhea virus S1 protein induced intestinal mucosal immune response in mice
by: Kai Su, et al.
Published: (2023-09-01)

The Mechanism of Action of the Active Ingredients of <i>Coptidis rhizoma</i> against Porcine Epidemic Diarrhea Was Investigated Using Network Pharmacology and Molecular Docking Technology
by: Hong Zou, et al.
Published: (2024-07-01)

Seroepidemiology Study of Porcine Epidemic Diarrhea Virus in Mexico by Indirect Enzyme-Linked Immunosorbent Assay Based on a Recombinant Fragment of N-Terminus Domain Spike Protein
by: Eduardo García-González, et al.
Published: (2023-07-01)

Recombinant <i>Lactobacillus casei</i> Expressing Capsid Protein VP60 can Serve as Vaccine Against Rabbit Hemorrhagic Disease Virus in Rabbits
by: Li Wang, et al.
Published: (2019-11-01)

Contribution of <i>Lactobacilli</i> on Intestinal Mucosal Barrier and Diseases: Perspectives and Challenges of <i>Lactobacillus casei</i>
by: Da Qin, et al.
Published: (2022-11-01)

Strategy of Developing Oral Vaccine Candidates Against Co-infection of Porcine Diarrhea Viruses Based on a Lactobacillus Delivery System
by: Tiantian Guo, et al.
Published: (2022-04-01)

Effect of Microencapsulation Techniques on the Stress Resistance and Biological Activity of Bovine Lactoferricin-Lactoferrampin-Encoding <i>Lactobacillus reuteri</i>
by: Xueying Wang, et al.
Published: (2022-10-01)

The spike glycoprotein genes of porcine epidemic diarrhea viruses isolated in China
by: Pei-Hua Wang, et al.
Published: (2021-06-01)

Analysis of Intestinal Mucosa Integrity and <i>GLP-2</i> Gene Functions upon Porcine Epidemic Diarrhea Virus Infection in Pigs
by: Yajing Zhou, et al.
Published: (2021-03-01)

Development and Immunogenicity Study of Subunit Vaccines Based on Spike Proteins of Porcine Epidemic Diarrhea Virus and Porcine Transmissible Gastroenteritis Virus
by: Mingguo Xu, et al.
Published: (2025-02-01)

A Nanobody of PEDV S1 Protein: Screening and Expression in <i>Escherichia coli</i>
by: Zhipeng Hao, et al.
Published: (2024-09-01)

Immune Responses Induced by Recombinant <i>Bacillus subtilis</i> Expressing the PEDV Spike Protein Targeted at Microfold Cells
by: Jian Lin, et al.
Published: (2022-04-01)

Development of an Indirect Enzyme-Linked Immunosorbent Assay Based on the Yeast-Expressed CO-26K-Equivalent Epitope-Containing Antigen for Detection of Serum Antibodies against Porcine Epidemic Diarrhea Virus
by: Xuqiong Yang, et al.
Published: (2023-03-01)

AEN Suppresses the Replication of Porcine Epidemic Diarrhea Virus by Inducing the Expression of Type I IFN and ISGs in MARC-145 Cells
by: Miao Luo, et al.
Published: (2023-12-01)

Genetic characterization of the spike gene of porcine epidemic diarrhea viruses (PEDVs) circulating in Vietnam from 2015 to 2016
by: Van T. Than, et al.
Published: (2020-08-01)

Mini-review: microbiota have potential to prevent PEDV infection by improved intestinal barrier
by: Shanshan Yang, et al.
Published: (2023-07-01)

Construction and immunogenicity of a trypsin-independent porcine epidemic diarrhea virus variant
by: Mingxiang Li, et al.
Published: (2023-03-01)

Display of Porcine Epidemic Diarrhea Virus Spike Protein on Baculovirus to Improve Immunogenicity and Protective Efficacy
by: Chia-Yu Chang, et al.
Published: (2018-06-01)

Single-Particle Tracking Porcine Epidemic Diarrhea Virus Moving along Microtubules in Living Cells
by: Yangyang Li, et al.
Published: (2020-07-01)

Immunogenicity evaluation of recombinant Lactobacillus casei W56 expressing bovine viral diarrhea virus E2 protein in conjunction with cholera toxin B subunit as an adjuvant
by: Shuo Jia, et al.
Published: (2020-10-01)

A novel biotinylated nanobody-based blocking ELISA for the rapid and sensitive clinical detection of porcine epidemic diarrhea virus
by: Zhiqian Ma, et al.
Published: (2019-09-01)

Novel Approach for Isolation and Identification of Porcine Epidemic Diarrhea Virus (PEDV) Strain NJ Using Porcine Intestinal Epithelial Cells
by: Wen Shi, et al.
Published: (2017-01-01)

Correction to: Immunogenicity evaluation of recombinant Lactobacillus casei W56 expressing bovine viral diarrhea virus E2 protein in conjunction with cholera toxin B subunit as an adjuvant
by: Shuo Jia, et al.
Published: (2022-10-01)

Oral Immunization of Chickens with Probiotic <em>Lactobacillus crispatus</em> Constitutively Expressing the α-β2-ε-β1 Toxoids to Induce Protective Immunity
by: Mohammad Zeb Khan, et al.
Published: (2022-04-01)

A <i>Taq</i>Man Probe-Based Multiplex Real-Time PCR for Simultaneous Detection of Porcine Epidemic Diarrhea Virus Subtypes G1 and G2, and Porcine Rotavirus Groups A and C
by: Letian Zhang, et al.
Published: (2022-08-01)

Oral Immunization against PEDV with Recombinant Lactobacillus casei Expressing Dendritic Cell-Targeting Peptide Fusing COE Protein of PEDV in Piglets
by: Xingyu Hou, et al.
Published: (2018-03-01)

Pathogenicity and Immunogenicity of a Serially Passaged Attenuated Genotype 2c Porcine Epidemic Diarrhea Virus Cultured in Suspended Vero Cells
by: Fei-Fei Ge, et al.
Published: (2022-04-01)

Hepatic Anti-Oxidative Genes <i>CAT</i> and <i>GPX4</i> Are Epigenetically Modulated by RORγ/NRF2 in Alphacoronavirus-Exposed Piglets
by: Haotian Gu, et al.
Published: (2023-06-01)