MicroRNA-106a Inhibits Autophagy Process and Antimicrobial Responses by Targeting ULK1, ATG7, and ATG16L1 During Mycobacterial Infection

MicroRNA-106a Inhibits Autophagy Process and Antimicrobial Responses by Targeting ULK1, ATG7, and ATG16L1 During Mycobacterial Infection

Autophagy is a key element of innate immune response against invading pathogens including Mycobacterium tuberculosis (M. tuberculosis). The emerging roles of microRNAs in regulating host antimicrobial responses against M. tuberculosis have gained widespread attention. However, the process by which m...

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Bibliographic Details
Main Authors: Kunmei Liu, Dantong Hong, Fan Zhang, Xin Li, Meng He, Xuebo Han, Guolin Zhang, Guangxian Xu, Nicola J. Stonehouse, Zhongjia Jiang, Weijun An, Le Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
Mycobacterium tuberculosis
autophagy
miR-106a
ULK1
ATG7
ATG16L1
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.610021/full

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