Construction and Validation of a 6-Ferroptosis Related Gene Signature for Prognosis and Immune Landscape Prediction in Melanoma

Construction and Validation of a 6-Ferroptosis Related Gene Signature for Prognosis and Immune Landscape Prediction in Melanoma

Ferroptosis is a newly discovered form of non-apoptotic cell death that relies on iron-mediated oxidative damage, playing a crucial role in the progression and therapy resistance of melanoma. Hence, the potential value of ferroptosis-related genes (FRGs) as a prognostic model and therapeutic target...

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Bibliographic Details
Main Authors: Zhanghui Yue, Jianfang Sun, Liqing Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
melanoma
ferroptosis
prognostic model
tumor-infiltrating immune cells
immunotherapy
immune checkpoints
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.887542/full

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