The temporal dedifferentiation of global brain signal fluctuations during human brain ageing

Abstract The variation of brain functions as healthy ageing has been discussed widely using resting-state brain imaging. Previous conclusions may be misinterpreted without considering the effects of global signal (GS) on local brain activities. Up to now, the variation of GS with ageing has not been...

Full description

Bibliographic Details
Main Authors: Yujia Ao, Juan Kou, Chengxiao Yang, Yifeng Wang, Lihui Huang, Xiujuan Jing, Qian Cui, Xueli Cai, Jing Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-07578-6