Infusion of bone marrow mononuclear cells reduces lung fibrosis but not inflammation in the late stages of murine silicosis.

Infusion of bone marrow mononuclear cells reduces lung fibrosis but not inflammation in the late stages of murine silicosis.

We hypothesized that infusion of bone marrow mononuclear cells (BMMCs) in the late stages of silica-induced damage would reduce the remodelling process in a murine model of silicosis. C57BL/6 mice were assigned to 2 groups. In the SIL group, mice were instilled with a silica particle suspension intr...

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Main Authors: Miquéias Lopes-Pacheco, Túlio G Ventura, Helena D'Anunciação de Oliveira, Leonardo C Monção-Ribeiro, Bianca Gutfilen, Sergio A L de Souza, Patrícia R M Rocco, Radovan Borojevic, Marcelo M Morales, Christina M Takiya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4192548?pdf=render

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