A fatal case of AIDS-defining meningoencephalitis by <it>C. Neoformans</it>, sensitive to antifungal therapy
<p>Abstract</p> <p><it>Cryptococcus neoformans </it>is the most common cause of life threatening meningoencephalitis in HIV-infected patients. Diagnosis is based on tests for cryptoccocal antigen in serum and cerebrospinal fluid, and on culture of the organism. We prese...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-11-01
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| Series: | European Journal of Medical Research |
| Subjects: | |
| Online Access: | http://www.eurjmedres.com/content/15/11/504 |
| _version_ | 1818759111227998208 |
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| author | Mohammad-Khani S Otremba B Klein R Capelle HH Logemann F Bange FC Schmidt RE Stoll M |
| author_facet | Mohammad-Khani S Otremba B Klein R Capelle HH Logemann F Bange FC Schmidt RE Stoll M |
| author_sort | Mohammad-Khani S |
| collection | DOAJ |
| description | <p>Abstract</p> <p><it>Cryptococcus neoformans </it>is the most common cause of life threatening meningoencephalitis in HIV-infected patients. Diagnosis is based on tests for cryptoccocal antigen in serum and cerebrospinal fluid, and on culture of the organism. We present a case of AIDS-related cryptococcal meningoencephalitis unresponsive to antifungal combination therapy, despite of evidence of fungal susceptibility in vitro. Significant decreases in cryptococcal antigen titers in serum and cerebrospinal fluid did not correlate with progress in disease and fatal outcome.</p> |
| first_indexed | 2024-12-18T06:37:32Z |
| format | Article |
| id | doaj.art-31233578fc0c4edb806e1e946355ae43 |
| institution | Directory Open Access Journal |
| issn | 2047-783X |
| language | English |
| last_indexed | 2024-12-18T06:37:32Z |
| publishDate | 2010-11-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj.art-31233578fc0c4edb806e1e946355ae432022-12-21T21:17:44ZengBMCEuropean Journal of Medical Research2047-783X2010-11-01151150410.1186/2047-783X-15-11-504A fatal case of AIDS-defining meningoencephalitis by <it>C. Neoformans</it>, sensitive to antifungal therapyMohammad-Khani SOtremba BKlein RCapelle HHLogemann FBange FCSchmidt REStoll M<p>Abstract</p> <p><it>Cryptococcus neoformans </it>is the most common cause of life threatening meningoencephalitis in HIV-infected patients. Diagnosis is based on tests for cryptoccocal antigen in serum and cerebrospinal fluid, and on culture of the organism. We present a case of AIDS-related cryptococcal meningoencephalitis unresponsive to antifungal combination therapy, despite of evidence of fungal susceptibility in vitro. Significant decreases in cryptococcal antigen titers in serum and cerebrospinal fluid did not correlate with progress in disease and fatal outcome.</p>http://www.eurjmedres.com/content/15/11/504Cryptococcal meningitisHIVantifungal therapycryptoccocal antigen assay |
| spellingShingle | Mohammad-Khani S Otremba B Klein R Capelle HH Logemann F Bange FC Schmidt RE Stoll M A fatal case of AIDS-defining meningoencephalitis by <it>C. Neoformans</it>, sensitive to antifungal therapy European Journal of Medical Research Cryptococcal meningitis HIV antifungal therapy cryptoccocal antigen assay |
| title | A fatal case of AIDS-defining meningoencephalitis by <it>C. Neoformans</it>, sensitive to antifungal therapy |
| title_full | A fatal case of AIDS-defining meningoencephalitis by <it>C. Neoformans</it>, sensitive to antifungal therapy |
| title_fullStr | A fatal case of AIDS-defining meningoencephalitis by <it>C. Neoformans</it>, sensitive to antifungal therapy |
| title_full_unstemmed | A fatal case of AIDS-defining meningoencephalitis by <it>C. Neoformans</it>, sensitive to antifungal therapy |
| title_short | A fatal case of AIDS-defining meningoencephalitis by <it>C. Neoformans</it>, sensitive to antifungal therapy |
| title_sort | fatal case of aids defining meningoencephalitis by it c neoformans it sensitive to antifungal therapy |
| topic | Cryptococcal meningitis HIV antifungal therapy cryptoccocal antigen assay |
| url | http://www.eurjmedres.com/content/15/11/504 |
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