Intrarenal Renin Angiotensin System Imbalance During Postnatal Life Is Associated With Increased Microvascular Density in the Mature Kidney

Intrarenal Renin Angiotensin System Imbalance During Postnatal Life Is Associated With Increased Microvascular Density in the Mature Kidney

Environmental stress during early life is an important factor that affects the postnatal renal development. We have previously shown that male rats exposed to maternal separation (MatSep), a model of early life stress, are normotensive but display a sex-specific reduced renal function and exacerbate...

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Bibliographic Details
Main Authors: Carolina Dalmasso, Alejandro R. Chade, Mariela Mendez, Jorge F. Giani, Gregory J. Bix, Kuey C. Chen, Analia S. Loria
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Physiology
Subjects:
maternal separation
kidney
renin-angiotensin system
microvascular density
renal transcriptome
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.01046/full

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