A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen.

A temperature-responsive network links cell shape and virulence traits in a primary fungal pathogen.

Survival at host temperature is a critical trait for pathogenic microbes of humans. Thermally dimorphic fungal pathogens, including Histoplasma capsulatum, are soil fungi that undergo dramatic changes in cell shape and virulence gene expression in response to host temperature. How these organisms li...

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Bibliographic Details
Main Authors: Sinem Beyhan, Matias Gutierrez, Mark Voorhies, Anita Sil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3720256?pdf=render

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