At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes

At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes

<p>Abstract</p> <p>Background</p> <p>Many sedative agents, including anesthetics, produce explicit memory impairment by largely unknown mechanisms. Sharp-wave ripple (SPW-R) complexes are network activity thought to represent the neuronal substrate for information trans...

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Bibliographic Details
Main Authors: Sotiriou Evangelos, Papatheodoropoulos Costas, Kotzadimitriou Dimitrios, Drimala Panagiota
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Neuroscience
Online Access:http://www.biomedcentral.com/1471-2202/8/60

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