Triple Assessment for the Diagnosis of Carcinoma Breast in a Tertiary Care Hospital of Tripura: A Cross-sectional Study
Introduction: A combination of invasive and non invasive procedures, clinical examination, radiological imaging {mammography/ultrasonography/Magnetic Resonance Imaging (MRI)} and Fine Needle Aspiration Cytology (FNAC) called the triple assessment test is being increasingly used in place of the more...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2022-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://www.jcdr.net/articles/PDF/16438/52732_CE[Ra1]_F[SH]_PF1(AKA_SS)_PFA(AKA_KM)_PN(KM)_PF2(AVG_SH_SL).pdf |
| Summary: | Introduction: A combination of invasive and non invasive procedures, clinical examination, radiological imaging {mammography/ultrasonography/Magnetic Resonance Imaging (MRI)} and Fine Needle Aspiration Cytology (FNAC) called the triple assessment test is being increasingly used in place of the more invasive core needle biopsy and histopathology.
Aim: To evaluate accuracy of triple assessment in the preoperative diagnosis of patients with breast carcinoma and to determine sensitivity and specificity with regards to histopathology in the diagnosis of the disease.
Materials and Methods: A cross-sectional study was conducted among 61 women of more than 25 years of age having palpable breast lump, attending the surgery Outpatient Department (OPD) and breast clinic of a tertiary care hospital from January 2017 to February 2019. Data on socio-demographic status, menstrual and obstetric information, clinical examination performed, mammography, FNAC, high resolution sonography breast and histopathology were recorded into predesigned and pretested proforma and analysed using Statistical Package for Social Sciences (SPSS) version 25.0.
Results: Out of total 61 patients participated in the present study, most patients were of 41-50 years of age, with a mean age of 44.23±7.4 years. Majority of patients were married, non vegetarian and without any past history of alcohol consumption. Sensitivity and specificity of triple assessment was 98.3% and 100%, respectively. The positive predictive value of triple assessment was 100% while the negative predictive value was 66.7%. All values were significantly better than both clinical breast examination and FNAC in detecting malignancies.
Conclusion: The triple test was also found to be accurate in diagnosing breast carcinoma in this geographical region. A patient with a negative triple test report can be safely followed-up without the need for biopsy. |
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| ISSN: | 2249-782X 0973-709X |