A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional activation of GAS6 and a set of SWI/SNF target genes.
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2020-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-14623-3 |
| _version_ | 1818851481619529728 |
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| author | Elena Grossi Ivan Raimondi Enrique Goñi Jovanna González Francesco P. Marchese Vicente Chapaprieta José I. Martín-Subero Shuling Guo Maite Huarte |
| author_facet | Elena Grossi Ivan Raimondi Enrique Goñi Jovanna González Francesco P. Marchese Vicente Chapaprieta José I. Martín-Subero Shuling Guo Maite Huarte |
| author_sort | Elena Grossi |
| collection | DOAJ |
| description | SWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional activation of GAS6 and a set of SWI/SNF target genes. |
| first_indexed | 2024-12-19T07:05:43Z |
| format | Article |
| id | doaj.art-312881ea5ccf4917ac2bc11fe60be750 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T07:05:43Z |
| publishDate | 2020-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-312881ea5ccf4917ac2bc11fe60be7502022-12-21T20:31:16ZengNature PortfolioNature Communications2041-17232020-02-0111111610.1038/s41467-020-14623-3A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regionsElena Grossi0Ivan Raimondi1Enrique Goñi2Jovanna González3Francesco P. Marchese4Vicente Chapaprieta5José I. Martín-Subero6Shuling Guo7Maite Huarte8Department of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research, University of NavarraDepartment of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research, University of NavarraDepartment of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research, University of NavarraDepartment of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research, University of NavarraDepartment of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research, University of NavarraDepartament de Fonaments Clinics, Facultat de Medicina, Universitat de BarcelonaDepartament de Fonaments Clinics, Facultat de Medicina, Universitat de BarcelonaDepartment of Antisense Drug Discovery and Clinical Development, Ionis PharmaceuticalsDepartment of Gene Therapy and Regulation of Gene Expression, Center for Applied Medical Research, University of NavarraSWI/SNF complexes regulate chromatin architecture and gene expression. Here the authors report the RNA interactome of SMARCB1-containing SWI/SNF complexes, showing the function of SMARCB1-interacting long noncoding RNA SWINGN in transcriptional activation of GAS6 and a set of SWI/SNF target genes.https://doi.org/10.1038/s41467-020-14623-3 |
| spellingShingle | Elena Grossi Ivan Raimondi Enrique Goñi Jovanna González Francesco P. Marchese Vicente Chapaprieta José I. Martín-Subero Shuling Guo Maite Huarte A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions Nature Communications |
| title | A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions |
| title_full | A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions |
| title_fullStr | A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions |
| title_full_unstemmed | A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions |
| title_short | A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions |
| title_sort | lncrna swi snf complex crosstalk controls transcriptional activation at specific promoter regions |
| url | https://doi.org/10.1038/s41467-020-14623-3 |
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