The SC-35 Splicing Factor Interacts with RNA Pol II and A-Type Lamin Depletion Weakens This Interaction

The SC-35 Splicing Factor Interacts with RNA Pol II and A-Type Lamin Depletion Weakens This Interaction

The essential components of splicing are the splicing factors accumulated in nuclear speckles; thus, we studied how DNA damaging agents and A-type lamin depletion affect the properties of these regions, positive on the SC-35 protein. We observed that inhibitor of PARP (<i>poly (ADP-ribose) pol...

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Bibliographic Details
Main Authors: Soňa Legartová, Paolo Fagherazzi, Lenka Stixová, Aleš Kovařík, Ivan Raška, Eva Bártová
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cells
Subjects:
splicing
SC-35
PARP inhibitor
RNA pol II
Online Access:https://www.mdpi.com/2073-4409/10/2/297

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