LysSYL: a broad-spectrum phage endolysin targeting Staphylococcus species and eradicating S. aureus biofilms

LysSYL: a broad-spectrum phage endolysin targeting Staphylococcus species and eradicating S. aureus biofilms

Abstract Background Staphylococcus aureus and its single or mixed biofilm infections seriously threaten global public health. Phage therapy, which uses active phage particles or phage-derived endolysins, has emerged as a promising alternative strategy to antibiotic treatment. However, high-efficient...

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Bibliographic Details
Main Authors: He Liu, Xuemei Wei, Zhefen Wang, Xiaonan Huang, Mengyang Li, Zhen Hu, Kexin Zhang, Qiwen Hu, Huagang Peng, Weilong Shang, Yi Yang, Yuting Wang, Shuguang Lu, Xiancai Rao
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Microbial Cell Factories
Subjects:
Phage
Endolysin
Staphylococcus aureus
Biofilms
Persisters
Online Access:https://doi.org/10.1186/s12934-024-02359-4

Internet

https://doi.org/10.1186/s12934-024-02359-4

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