Increase in the Level of Proinflammatory Cytokine HMGB1 in Nasal Fluids of Patients With Rhinitis and its Sequestration by Glycyrrhizin Induces Eosinophil Cell Death

Increase in the Level of Proinflammatory Cytokine HMGB1 in Nasal Fluids of Patients With Rhinitis and its Sequestration by Glycyrrhizin Induces Eosinophil Cell Death

ObjectivesThe nuclear protein high mobility group protein box 1 (HMGB1) is a proinflammatory mediator that belongs to the alarmin family of proinflammatory mediators, and it has recently emerged as a key player in different acute and chronic immune disorders. Several lines of evidence demonstrate th...

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Bibliographic Details
Main Authors: Leonardo Cavone, Caterina Cuppari, Sara Manti, Luisa Grasso, Teresa Arrigo, Luca Calamai, Carmelo Salpietro, Alberto Chiarugi
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2015-06-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Rhinitis
Eosinophils
HMGB1 protein
Glycyrrhizin acid
Online Access:http://www.e-ceo.org/upload/pdf/ceo-8-123.pdf

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