Identification of Novel Artemisinin Hybrids Induce Apoptosis and Ferroptosis in MCF-7 Cells

Identification of Novel Artemisinin Hybrids Induce Apoptosis and Ferroptosis in MCF-7 Cells

A series of novel 1,3,4-oxadiazole-artemisinin hybrids have been designed and synthesized. An MTT assay revealed that most of tested hybrids showed more enhanced anti-proliferative activities than artemisinin, among which A8 had the superior potency with IC<sub>50</sub> values ranging fr...

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Bibliographic Details
Main Authors:	Ye Zhong, Zhi-Ning Li, Xin-Yue Jiang, Xing Tian, Ming-Hui Deng, Mao-Sheng Cheng, Hua-Li Yang, Yang Liu
Format:	Article
Language:	English
Published:	MDPI AG 2022-12-01
Series:	International Journal of Molecular Sciences
Subjects:	1,3,4-oxadiazole artemisinin apoptosis ferroptosis antitumor
Online Access:	https://www.mdpi.com/1422-0067/23/24/15768

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