Oxymatrine Alleviates Gentamicin-Induced Renal Injury in Rats

Oxymatrine Alleviates Gentamicin-Induced Renal Injury in Rats

Gentamicin is an aminoglycoside antibiotic commonly used to treat Gram-negative bacterial infections that possesses considerable nephrotoxicity. Oxymatrine is a phytochemical with the ability to counter gentamicin toxicity. We investigated the effects and protective mechanism of oxymatrine in rats....

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Bibliographic Details
Main Authors: Songyao Kang, Tingting Chen, Zhihui Hao, Xiao Yang, Mingfa Wang, Zhifang Zhang, Sijia Hao, Fengting Lang, Hongxia Hao
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Molecules
Subjects:
gentamicin
nephrotoxicity
oxymatrine
oxidative stress
Nrf2/HO-1
Online Access:https://www.mdpi.com/1420-3049/27/19/6209

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