RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation

RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation

Summary: R-spondin 2 (RSPO2) drives the potentiation of Wnt signaling and is implicated in tumorigenesis in multiple cancers, but its role in ovarian cancer has not been investigated. Here, we reported that RSPO2 promoted the growth and metastasis of ovarian cancer through the activation of FAK/Src...

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Bibliographic Details
Main Authors: Rulu Pan, Yan Yu, Haiyan Zhu, Wenyi Zhang, Yuan Qin, Lin Ye, Juji Dai, Ren Huang, Xinyan Peng, Siqi Ye, Ziqi Lin, Shishun Huang, Shuyi Chong, Liting Lu, Xincheng Lu
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Cell biology
cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222014560

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