Garlic and Resveratrol attenuate diabetic complications, loss of β-cells, pancreatic and hepatic oxidative stress in streptozotocin-induced diabetic rats

Garlic and Resveratrol attenuate diabetic complications, loss of β-cells, pancreatic and hepatic oxidative stress in streptozotocin-induced diabetic rats

Abstract:The study was aimed at finding the effect of garlic and resveratrol on loss of β-cells and diabetic complication in streptozotocin (STZ)-induced Type-I diabetic rats. Rats were injected with single dose STZ (50mg/kg, i.p.) for induction of type 1 diabetes (Dia) and compared with control gro...

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Bibliographic Details
Main Authors: Gagandeep Kaur, Raju Padiya, Ramu Adela, Uday Kumar Putcha, Sweeya Reddy, Raghunath Reddy, Praveen Kumar, Sumana Chakravarty, Sanjay Kumar Banerjee
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Pharmacology
Subjects:
Metformin
resveratrol
type 1 diabetes
beta cells
STZ-induced diabetes
Type-I diabetes; STZ; garlic; resveratrol; metformin; beta cell.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00360/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00360/full

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