Nitric oxide-dependent immunosuppressive function of thymus-derived mesenchymal stromal/stem cells

Nitric oxide-dependent immunosuppressive function of thymus-derived mesenchymal stromal/stem cells

Abstract Background The thymus is required for T cell development and the formation of the adaptive immunity. Stromal cells, which include thymic epithelial cells (TECs) and mesenchymal stromal cells (MSCs), are essential for thymic function. However, the immunomodulatory function of thymus-derived...

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Main Authors: Xiao Su, Xiaolei Li, Shiqing Wang, Xiaotong Xue, Rui Liu, Xiaojing Bai, Pixia Gong, Chao Feng, Lijuan Cao, Tingting Wang, Yayun Ding, Junjie Jiang, Yongjing Chen, Yufang Shi, Changshun Shao
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Biology Direct
Subjects:
Thymus
Mesenchymal stromal/stem cells
Immunomodulation
NO
Nestin
Online Access:https://doi.org/10.1186/s13062-023-00415-4

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