Sliding to the rescue of damaged DNA

Single-molecule imaging experiments have shed new light on the methods used by the enzyme RecA to align single- and double-stranded DNA so that double-strand breaks can be repaired.

Bibliographic Details
Main Authors: Bryan Gibb, Eric C Greene
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2012-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00347
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author Bryan Gibb
Eric C Greene
author_facet Bryan Gibb
Eric C Greene
author_sort Bryan Gibb
collection DOAJ
description Single-molecule imaging experiments have shed new light on the methods used by the enzyme RecA to align single- and double-stranded DNA so that double-strand breaks can be repaired.
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spelling doaj.art-312d7a70a26b4e8fa3498aa917d805732022-12-22T02:02:45ZengeLife Sciences Publications LtdeLife2050-084X2012-12-01110.7554/eLife.00347Sliding to the rescue of damaged DNABryan Gibb0Eric C Greene1Department of Biochemistry and Molecular Biophysics, and the Howard Hughes Medical Institute, Columbia University, New York, United StatesDepartment of Biochemistry and Molecular Biophysics, and the Howard Hughes Medical Institute, Columbia University, New York, United StatesSingle-molecule imaging experiments have shed new light on the methods used by the enzyme RecA to align single- and double-stranded DNA so that double-strand breaks can be repaired.https://elifesciences.org/articles/00347Single MoleculeFRETDNA repairHomologous Recombination
spellingShingle Bryan Gibb
Eric C Greene
Sliding to the rescue of damaged DNA
eLife
Single Molecule
FRET
DNA repair
Homologous Recombination
title Sliding to the rescue of damaged DNA
title_full Sliding to the rescue of damaged DNA
title_fullStr Sliding to the rescue of damaged DNA
title_full_unstemmed Sliding to the rescue of damaged DNA
title_short Sliding to the rescue of damaged DNA
title_sort sliding to the rescue of damaged dna
topic Single Molecule
FRET
DNA repair
Homologous Recombination
url https://elifesciences.org/articles/00347
work_keys_str_mv AT bryangibb slidingtotherescueofdamageddna
AT ericcgreene slidingtotherescueofdamageddna