Sliding to the rescue of damaged DNA
Single-molecule imaging experiments have shed new light on the methods used by the enzyme RecA to align single- and double-stranded DNA so that double-strand breaks can be repaired.
Main Authors: | , |
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Format: | Article |
Language: | English |
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eLife Sciences Publications Ltd
2012-12-01
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Series: | eLife |
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Online Access: | https://elifesciences.org/articles/00347 |
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author | Bryan Gibb Eric C Greene |
author_facet | Bryan Gibb Eric C Greene |
author_sort | Bryan Gibb |
collection | DOAJ |
description | Single-molecule imaging experiments have shed new light on the methods used by the enzyme RecA to align single- and double-stranded DNA so that double-strand breaks can be repaired. |
first_indexed | 2024-12-10T04:10:19Z |
format | Article |
id | doaj.art-312d7a70a26b4e8fa3498aa917d80573 |
institution | Directory Open Access Journal |
issn | 2050-084X |
language | English |
last_indexed | 2024-12-10T04:10:19Z |
publishDate | 2012-12-01 |
publisher | eLife Sciences Publications Ltd |
record_format | Article |
series | eLife |
spelling | doaj.art-312d7a70a26b4e8fa3498aa917d805732022-12-22T02:02:45ZengeLife Sciences Publications LtdeLife2050-084X2012-12-01110.7554/eLife.00347Sliding to the rescue of damaged DNABryan Gibb0Eric C Greene1Department of Biochemistry and Molecular Biophysics, and the Howard Hughes Medical Institute, Columbia University, New York, United StatesDepartment of Biochemistry and Molecular Biophysics, and the Howard Hughes Medical Institute, Columbia University, New York, United StatesSingle-molecule imaging experiments have shed new light on the methods used by the enzyme RecA to align single- and double-stranded DNA so that double-strand breaks can be repaired.https://elifesciences.org/articles/00347Single MoleculeFRETDNA repairHomologous Recombination |
spellingShingle | Bryan Gibb Eric C Greene Sliding to the rescue of damaged DNA eLife Single Molecule FRET DNA repair Homologous Recombination |
title | Sliding to the rescue of damaged DNA |
title_full | Sliding to the rescue of damaged DNA |
title_fullStr | Sliding to the rescue of damaged DNA |
title_full_unstemmed | Sliding to the rescue of damaged DNA |
title_short | Sliding to the rescue of damaged DNA |
title_sort | sliding to the rescue of damaged dna |
topic | Single Molecule FRET DNA repair Homologous Recombination |
url | https://elifesciences.org/articles/00347 |
work_keys_str_mv | AT bryangibb slidingtotherescueofdamageddna AT ericcgreene slidingtotherescueofdamageddna |