Homer 1 genotype AA variant relates to congenital splay leg syndrome in piglets by repressing Pax7 in myogenic progenitors

Homer 1 genotype AA variant relates to congenital splay leg syndrome in piglets by repressing Pax7 in myogenic progenitors

IntroductionPorcine congenital splay leg syndrome (PCS) is a major birth defect in piglets, resulting in lameness and high mortality rates. The multifactorial pathogenesis of PSC is not well understood but includes a polygenic inheritance.MethodsHere, in addition to morphological investigations, we...

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Bibliographic Details
Main Authors: Toni Schumacher, Henry Reyer, Steffen Maak, Monika Röntgen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Veterinary Science
Subjects:
porcine congenital splay leg
PCS
SNP
homer1
myogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1028879/full

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