Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria
The objective of this paper was to determine the effect of tamsulosin use on plasma insulin status in benign prostatic hyperplasia (BPH) patients in Sokoto, Nigeria. Standard methods and procedures were used. At 2nd and 3rd months of tamsulosin use, there was a significant increase (P<0.05) in p...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)
2020-05-01
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| Series: | Journal of Applied Sciences and Environmental Management |
| Subjects: | |
| Online Access: | https://www.ajol.info/index.php/jasem/article/view/196068 |
| _version_ | 1797228082449350656 |
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| author | M Dikko S.O. Bello A. Chika I.A. Mungadi Y. Sarkingobir A.I. Umar |
| author_facet | M Dikko S.O. Bello A. Chika I.A. Mungadi Y. Sarkingobir A.I. Umar |
| author_sort | M Dikko |
| collection | DOAJ |
| description |
The objective of this paper was to determine the effect of tamsulosin use on plasma insulin status in benign prostatic hyperplasia (BPH) patients in Sokoto, Nigeria. Standard methods and procedures were used. At 2nd and 3rd months of tamsulosin use, there was a significant increase (P<0.05) in plasma insulin values compared to baseline. Likewise, at 4th month of tamsulosin use, a significant increase (P<0.05) in plasma insulin values was revealed compared to baseline and 2nd month values. Other inter-mean values comparisons were not significantly different (P>0.05). Plasma insulin at 4th months of the study in BPH patients (45-54 years) treated with tamsulosin revealed a significant increase (P<0.05) compared to baseline values. Other inter-mean values comparisons were not significantly different (P>0.05). BPH patients (aged 55-64 years) at 3rd month showed a significant increase (P<0.05) in plasma insulin values compared to baseline values. Likewise, at 4th month of tamsulosin use, a significant increase (P<0.05) in plasma insulin values was seen compared to baseline and 1st month values. Other inter-mean values comparisons were not significantly different (P>0.05). In BPH patients aged 65 and above, there was no significant difference (P>0.05) in plasma insulin values from 1st through 4th month compared to baseline and other inter mean values comparisons. Plasma insulin at 0th , 1st , 2nd , 3rd and 4th months of BPH patients of different age groups treated with tamsulosin revealed no significant differences (P>0.05). This study revealed that tamsulosin use in the patients lead to significant increase in plasma insulin level (hyperinsulinemia). Careful and routine monitoring of BPH patients should be done. Patients need enough exercise activities and some drugs can be administered to alleviate elevated glucose or insulin.
Keywords: Tamsulosin, hyperinsulinemia, benign prostatic hyperplasia patients, insulin resistance
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| first_indexed | 2024-04-24T14:51:02Z |
| format | Article |
| id | doaj.art-313233b92e6b4055bfee702b4c2881ea |
| institution | Directory Open Access Journal |
| issn | 2659-1502 2659-1499 |
| language | English |
| last_indexed | 2024-04-24T14:51:02Z |
| publishDate | 2020-05-01 |
| publisher | Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) |
| record_format | Article |
| series | Journal of Applied Sciences and Environmental Management |
| spelling | doaj.art-313233b92e6b4055bfee702b4c2881ea2024-04-02T19:49:31ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992020-05-0124410.4314/jasem.v24i4.1Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, NigeriaM DikkoS.O. BelloA. ChikaI.A. MungadiY. SarkingobirA.I. Umar The objective of this paper was to determine the effect of tamsulosin use on plasma insulin status in benign prostatic hyperplasia (BPH) patients in Sokoto, Nigeria. Standard methods and procedures were used. At 2nd and 3rd months of tamsulosin use, there was a significant increase (P<0.05) in plasma insulin values compared to baseline. Likewise, at 4th month of tamsulosin use, a significant increase (P<0.05) in plasma insulin values was revealed compared to baseline and 2nd month values. Other inter-mean values comparisons were not significantly different (P>0.05). Plasma insulin at 4th months of the study in BPH patients (45-54 years) treated with tamsulosin revealed a significant increase (P<0.05) compared to baseline values. Other inter-mean values comparisons were not significantly different (P>0.05). BPH patients (aged 55-64 years) at 3rd month showed a significant increase (P<0.05) in plasma insulin values compared to baseline values. Likewise, at 4th month of tamsulosin use, a significant increase (P<0.05) in plasma insulin values was seen compared to baseline and 1st month values. Other inter-mean values comparisons were not significantly different (P>0.05). In BPH patients aged 65 and above, there was no significant difference (P>0.05) in plasma insulin values from 1st through 4th month compared to baseline and other inter mean values comparisons. Plasma insulin at 0th , 1st , 2nd , 3rd and 4th months of BPH patients of different age groups treated with tamsulosin revealed no significant differences (P>0.05). This study revealed that tamsulosin use in the patients lead to significant increase in plasma insulin level (hyperinsulinemia). Careful and routine monitoring of BPH patients should be done. Patients need enough exercise activities and some drugs can be administered to alleviate elevated glucose or insulin. Keywords: Tamsulosin, hyperinsulinemia, benign prostatic hyperplasia patients, insulin resistance https://www.ajol.info/index.php/jasem/article/view/196068Tamsulosin, hyperinsulinemia, benign prostatic hyperplasia patients, insulin resistance |
| spellingShingle | M Dikko S.O. Bello A. Chika I.A. Mungadi Y. Sarkingobir A.I. Umar Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria Journal of Applied Sciences and Environmental Management Tamsulosin, hyperinsulinemia, benign prostatic hyperplasia patients, insulin resistance |
| title | Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria |
| title_full | Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria |
| title_fullStr | Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria |
| title_full_unstemmed | Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria |
| title_short | Effect of Tamsulosin Use on Plasma Insulin Status in Benign Prostatic Hyperplasia Patients in Sokoto, Nigeria |
| title_sort | effect of tamsulosin use on plasma insulin status in benign prostatic hyperplasia patients in sokoto nigeria |
| topic | Tamsulosin, hyperinsulinemia, benign prostatic hyperplasia patients, insulin resistance |
| url | https://www.ajol.info/index.php/jasem/article/view/196068 |
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